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"The aim of the experiment is to experimentally establish the accuracy of long-term blood pressure measurements with a Samsung smart watch from two consecutive calibrations over a period of 28 days in comparison with a digital tonometer that has been designated as a medical device. " Volunteers will monitor blood pressure and heart rate manually twice a day from a smartwatch and a digital tonometer simultaneously twice a day.
Source link: https://clinicaltrials.gov/ct2/show/NCT05401435
"Background: Emerging evidence supports aortic blood pressure over brachial cuff BP in predicting CV and renal issues, as this BP directly affects the heart, brain, and kidneys. In parallel, central BP measurement systems have been developed that are more accurate toward aortic BP and are simpler to use without training. Undertreatment is also associated with adverse CV events and progression to end-stage kidney disease, causing adverse CV events and painful falls, but also acute kidney injury, which can cause ESKD. Given that these patients have a high risk of CV morbidity and mortality, and are a group in which brachial BP is the least accurate, it could be beneficial to treat hypertension in this population using central BP measurements. With the introduction of inexpensive and simple to use central BP devices, regular use of central BP hypertension has now become a possibility. However, the superiority of central BP to traditional brachial cuff BP in terms of clinical outcomes will first have to be demonstrated. After 12 months of follow-up, the aim is to demonstrate that targeting central BP in advanced CKD patients as opposed to brachial cuff BP is feasible and results in reduced arterial stiffness. Patients with CKD stages 4 and 5 will be randomized to either a central systolic BP target 130 mmHg or brachial systolic BP target 130 mmHg. ".
Source link: https://clinicaltrials.gov/ct2/show/NCT05163158
"From 1994-2003, stroke mortality in ANAIs was at least 25% higher than in Whites in Alaska. " A significant rise in recorded prevalence among ANAI people over the past three decades has been documented, as well as a significantly higher risk of ANAI adults than in reference populations, mainly White. Aggregated results from the Behavioral Risk Factor Surveillance System reveal a higher risk of self-reported hypertension in ANAIs than in non-Hispanic Whites. Ongoing monitoring of elevated BP often requires healthcare providers to introduce or intensify therapy in response to uncontrolled high blood pressure. After a computer-generated alert, more than half of physicians with hypertension had poorly managed systolic BP, according to another study based on military veteran blood pressure data, although only 51% of patients with hypertension had poorly controlled systolic BP. Patients must be seen outside the clinic, "where patients are"" outside the clinic; support BP self-management; and minimize barriers to care are all a component of healthcare. AN/AIs face in healthcare are the same. In patients with less well-controlled BP at baseline, HBPM drugs appear to be the most cost-effective in patients with less well-controlled BP. It will be the first comprehensive, population-based study on BP control for prevention of CVD and stroke in ANs, and one of the few multilevel interventions in any minority group. Randomizing all SCF primary care panels to the BP-ICAN or standard care control arms will result in randomization of adult hypertension within groups designated by panel; adults with uncontrolled hypertension will be nested within groups designated by panel, which corresponds to one provider. " "For each panel, investigators will recruit up to ten ANAI adults with systolic BP u2265 130 mmHg determined at the study screening or home screening visit. " Participants in the BP-ICAN arm will be sent information about BP control, CVD, and stroke, as well as other lifestyle changes that can reduce or eliminate morbidity from hypertension, as well as educational information regarding the importance of timely reaction to uncontrolled hypertension. Participants in the BP-ICAN arm will also receive HBPM equipment and training in its use, interpretation of results, and assistance in conveying high BP values to healthcare practitioners. Investigators intend to use a cloud-based technology platform to act as a data repository and are consulting with tribal chief, institutional privacy officers, compliance officers, and service providers on how data will be displayed and stored within the health care system. The aim is to make aggregate BP measurement data available to providers in either a personal health record and/or health information exchange that allows for the exchange of select measures into the electronic health and/or population health database. The primary outcome is a change in systolic BP for all adults with hypertension whose providers are randomly assigned to the BP-ICAN arm vs. the care as usual arm, regardless of whether the adults were enrolled in the program directly.
Source link: https://clinicaltrials.gov/ct2/show/NCT03872856
"For each hospital stay participants, you will be required to arrive in the afternoon and remain until the next evening. " If they are taking any blood pressure medications, they will continue to take it through the analysis. Blood pressure will be monitored continuously during in-hospital stays using two small finger cuffs. Small gold-coated disks called electrodes will be placed on the head and body in order to monitor and record brain waves to determine sleep and wakefulness. Before and during the in-hospital stays, questions regarding sleep times, subjective sleepiness, and other indices related to well-being will be asked.
Source link: https://clinicaltrials.gov/ct2/show/NCT03043963
"Excessive dietary salt intake is correlated with an elevated risk of cardiovascular disease. " The reasons that underlie blood pressure's salt tolerance are still unclear. Chronically elevated salt and fructose intake alone have been shown to have adverse effects on the body, but the combination of salt and fructose has not been fully investigated in humans. In a population with normal blood pressure, knowing how the body regulates blood pressure in times of elevated salt and fructose is crucial in determining cardiovascular risk in a population with normal blood pressure. ".
Source link: https://clinicaltrials.gov/ct2/show/NCT04994418
"Most patients with End Stage Renal Disease will need haemodialysis. " Several research have shown that a well-functioning Arterio-Venous Fistula is the most effective method of accessing patients with ESRD undergoing haemodialysis. In comparison to the other two commonly available modalities of the Arterio-Venous Graft and Central Venous Catheter, a mature AVF has a reduced incidence of thrombosis and stenosis. In addition, lower mortality and costs have been tied to the use of AVF's. The aim of the research is to investigate the relationship between the pressure gradient within the surgically produced AVF and its maturation and functioning status. ".
Source link: https://clinicaltrials.gov/ct2/show/NCT04293614
"Hypertension or elevated blood pressure is a common and significant risk factor for heart disease and stroke in seven million people in Canada, costing the Canadian health care system approximately $20 billion per year. " To moderately lower blood pressure, the most common exercise plan for people with hypertension is to do aerobic exercises as a non-pharmacological way to moderately reduce blood pressure. Flexible training may result in more healthy blood pressure improvements than aerobic training, according to several new studies. This research involves a random controlled trial of 96 men and women with either elevated blood pressure or stage 1 hypertension stratified by blood pressure, sex, and age, and randomly assigned to one of two groups for six months: 1 a flexibility program 30 minutes of brisk walking per day; or 2 an aerobic training program 30 minutes of brisk walking per day.
Source link: https://clinicaltrials.gov/ct2/show/NCT05252208
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