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Bipolar Disorder - U.S. Department of Veterans Affairs

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Last Updated: 15 May 2022

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Lipophilic vs. hydrophilic statins and psychiatric hospitalizations and emergency room visits in US Veterans with schizophrenia and bipolar disorder.

We aimed to compare the relative risks of psychiatric hospitalizations and ED visits between individuals prescribed lipophilic vs. no statins vs. no statins, as well as the immune and kynurenine triggering of bipolar disorder and schizophrenia, as well as statin-modulatory effects of statins.

Source link: https://doi.org/10.1515/pteridines-2020-0028


Distinct patterns of altered quantitative T1ρ and functional BOLD response associated with history of suicide attempts in bipolar disorder.

Despite the high risk of suicide, very few studies have investigated the correlation between suicide and brain imaging techniques in bipolar disorder. In addition, no studies have investigated the possibility that altered brain metabolism may be related to suicide attempts. We investigated the psychological and metabolic differences associated with suicide attempt in bipolar disorder sufferers. To start filling these gaps, we looked at functional and metabolic characteristics. During a flashing checkerboard test, Thirty-nine participants with bipolar disorder underwent fMRI, and 27 people with quantitative T1 were included. Participants who had attempted suicide had greater fMRI task-related stimulation in visual areas and the cerebellum. Measures of suicide history may have been owing to statistical uncertainties. Some with and without suicide attempts differed from results obtained using a number of suicide attempts, indicating that these variables have different neurobiological underpinnings.

Source link: https://doi.org/10.1007/s11682-021-00552-2

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions