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Bioengineering - DOAJ

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Last Updated: 10 January 2023

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FAIR research data management as community approach in bioengineering

It was also demonstrated how FAIR 2010RDM can be implemented in a joint effort and the use of a data framework, according to a biotechnology research network with over 20 tandem projects. In addition, the value of a repository within a repository was shown to maintain biotechnology research results open throughout the entire data lifecycle. In addition, the biotechnology research network highlighted the importance of a network within a repository to make research data available throughout the entire data lifecycle.

Source link: https://doi.org/10.1002/elsc.202200005


Decellularization of the mouse ovary: comparison of different scaffold generation protocols for future ovarian bioengineering

The present research used the intact mouse ovary to create a mouse ovarian scaffold with various methods of decellularization. Material and methods Potentially immunogenic DNA and intracellular components were removed from whole mouse ovaries by agitation in a 0. 5 percent sodium dodecyl sulfate solution, a 2% sodium deoxycholate solution, or a combination of the two forms. Sodium dodecyl sulfate effectively removed DNA and intracellular components from the ovarian tissue, but it also significantly decreased the ovarian extracellular matrix's remaining intact. The sodium deoxycholate-generated ovarian scaffolds had higher donor DNA content, but they maintained the extracellular structure better, allowing for improved recellularization and other downstream bioengineering applications. These two new breeds of mouse ovarian scaffolds serve as promising scaffold-candidates for future ovarian bioengineering experiments.

Source link: https://doi.org/10.1186/s13048-019-0531-3


Assessing Data Management Support Needs of Bioengineering and Biomedical Research Faculty

Objectives : This report explores data management skills, attitudes, and practices of bioengineering and biomedical researchers in the context of the National Institutes of Health-funded research projects. To what extent are biomedical and bioengineering researchers aware of best practices for data processing, and what are the actual data processing habits? To what extent are biomedical and bioengineering researchers aware of data sharing opportunities and data repositories, and what are their views on data sharing? Methods : Librarians on the University of Illinois' Urbana Champaign campus conducted semi-structured interviews with bioengineering and biomedical researchers to determine data management best practices, awareness of library campus services, data processing strategies, and challenges managing research data. Current research findings, data types, shape, description, campus repository use, data sharing, and knowledge of library campus services, data reuse, and potential impacts of health on public and challenges were all discussed during the interviews. About half of the researchers interviewed reported having documented procedures for file names, file backup, and file storage. Findings also show that there is also ambiguity regarding what it means to publish research results and confusion regarding terms such as "u201crepository" and "u201cdata deposit"u201d. Conclusions : The interviews revealed significant data literacy gaps in library instruction, which include file organization, project management and documentation, metadata standards, and data deposit options.

Source link: https://doi.org/10.7191/jeslib.2019.1132


Closing the Gap between Bio-Based and Petroleum-Based Plastic through Bioengineering

Bioplastics, which are plastic materials made from renewable bio-based feedstocks, have been tested for their ability as an effective alternative to petroleum-based plastics. Despite the detrimental effects of plastic buildup in the atmosphere, bioplastic manufacturing in the United States is still underdeveloped. In addition, we also have extensive data on bacteria that produce PHAs and PHBs. As a viable production platform, we conclude that we also discuss the possibility of using large-scale genome engineering to create strains and isolate microalgae.

Source link: https://doi.org/10.3390/microorganisms10122320


Bioengineering Liver Organoids for Diseases Modelling and Transplantation

One must produce liver organoids with all the main liver cell types in appropriate proportions and relative 3D locations as found in a native liver in order to recapitulate the physiological characteristics and the architecture of a native liver. Here, we review the current liver organoid systems, focusing on the design of the liver organoid system, the role of growth factors for engineering liver organoids, as well as the latest developments in the bioengineering liver organoid disease models and their biomedical applications.

Source link: https://doi.org/10.3390/bioengineering9120796


Bioengineering to Accelerate Biodiesel Production for a Sustainable Biorefinery

Biodiesel has a similar chemical structure and combustion characteristics to fossil diesel, and therefore can be used as an energy source at the commercial level. To improve biodiesel production and maintain its sustainability, it is important to investigate new approaches, feedstock, and technologies since biodiesel is made using edible/non-edible crops has ignited questions regarding food vs. fuel, rising production cost, monocropping issue, and unintended environmental implications, such as land use patterns. A life cycle assessment will not only provide a better understanding of the various strategies for biodiesel production and waste valorization in the biorefinery model to determine the most effective method for biodiesel manufacturing, but also indicate a new vision for biodiesel adoption and commercialization of biodiesel.

Source link: https://doi.org/10.3390/bioengineering9110618

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions