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Binge eating disorder, the most common formal eating disorder, is strongly associated with obesity and bio-psychosocial impairment. This research is designed to determine the success of behavioral weight loss and pharmacological therapy with Naltrexone/Bupropion, both alone and in combination, for obesity-treatment in patients with obesity. New results regarding the use of NB medications and whether this particular combination of BWL and NB medication is safe for patients with obesity and BED will be published soon. RCT stands for emergency treatment stage stage.
Source link: https://clinicaltrials.gov/ct2/show/NCT03045341
Eating disorders affect 15 million people in the United States and have one of the highest mortality rates of any mental disorder. Using quantitative magnetic resonance imaging and behavioral analysis, the goal of this research is to investigate the effect of ovarian hormone stabilization, which has continued use of oral contraceptives for three months, on brain stimulation in response to reward and eating habits in women who binge eat. Participants will complete fMRI imaging and self-report questionnaires prior to the OC election and at the end of the OC administration. Aim 1: Measure the effect of ovarian hormone stability on eating habits in women with binge eating. Examine the effects of ovarian hormone stabilization on response to praise using fMRI and self-report questionnaires in women with binge eating.
Source link: https://clinicaltrials.gov/ct2/show/NCT04278755
15 million women in the United States experience eating disorders and have one of the highest mortality rates of any mental disorder in the United States. Bulimia nervosa (British) is a medical condition that causes researchers to investigate the direct and mechanistic role of E2 and P4 on binge eating in women with bulimia nervosa. BN is a hormone-sensitive phenotype, and this sensitivity is modulated by E2's influence on aspects of the reward response, such as reward-motivated behaviours in the context of low E2. Aim 1: Aim 1: Determine the immediate effects of E2 and P4 on binge eating in women with BN. Aim 2: Determine the effect of E2 on females with BN as a reward response. Aim 3: The correlation between reward response and binge eating before and after the E2 recall is examined.
Source link: https://clinicaltrials.gov/ct2/show/NCT04225221
Binge Eating Disorder has been incorporated into the Diagnostic and Statistical Manual 5 psychiatric classification and its severity criteria are still not well understood.
Source link: https://clinicaltrials.gov/ct2/show/NCT05149859
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