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Benign Tumors - Europe PMC

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Last Updated: 02 July 2022

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Demographic Profile of Benign and Malignant Oral Tumors in Central India: A Retrospective Comparative Study

In India, there are few studies comparing the demographic profile of benign and malignant oral tumors. Methods: This retrospective review examined biopsy results of patients with solid tumors who presented to the Oral and Maxillofacial Surgery department from 2006 to 2018. fibromas of various sorts and odontogenic tumors were the most common among benign tumors, among the benign tumors, and odontogenic tumors were the most common; among the malignant tumors, squamous cell carcinoma was the most common. Patients with malignant tumors were significantly older than benign tumors, according to the mean age of patients with malignant tumors, which was much higher than benign tumors. The median age of malignant oral tumors in patients under the age of 60 is 51 years, with almost one-fourth of all oral malignancies occurring in patients under 40 years old. In India, the high incidence of younger patients developing oral cancer has prompted urgent steps to raise concerns of oral cancer and its causative factors.

Source link: https://europepmc.org/article/MED/PMC9233233


Comparison of infectious complications after spleen preservation versus splenectomy during laparoscopic distal pancreatectomy for benign or low-grade malignant pancreatic tumors: A multicenter, propensity score-matched analysis.

According to propensity score matching results, LDP with splenectomy and LDP with spleen preservation were compared between LDP with splenectomy and LDP with spleen preservation. Conclusions After PSM, the LSPDP group had a reduced prevalence of overall infectious diseases and an elevated incidence of intraabdominal abscess relative to the LDPS group. The vessel preservation subgroup of the LSPDP had a significantly higher risk of infectious diseases within the LSPDP organization than the vessel resection subgroup. A greater incidence of intraabdominal abscess in low-volume centers in the LSPDP and the splenic vessel preservation subgroup was observed in the LSPDP and the splenic vessel preservation subgroup.

Source link: https://europepmc.org/article/MED/35766108


Clinico-Pathological Characteristics, Management, and Outcome of Benign Intraosseous Maxillary Tumors in Adolescents: A Prospective Study.

It is unusual to see Maxillary defect reconstruction in adolescents. Patients aged 12-18 years who developed benign intraosseous maxillary tumors and surgically treated with immediate reconstruction were included in the 10-year prospective study. Results Study included 38 patients; 62% had non-odontogenic tumors, and 36. 8% had odontogenic tumors, and 36. 8% had odontogenic tumors; 65% had non-odontogenic tumors; and 36. 8% had odontogenic tumors; and 36. 8% had odontogenic tumors. Central giant cell granuloma was the most common non-odontogenic tumor. Adenomatoid odontogenic tumor and ameloblastoma were two of the most common odontogenic tumors, as well as ameloblastoma. In 17 cases by temporalis muscle flap, obturator, and free fibula flap, reconstruction was successful. Conclusions Non-odontogenic tumors were more common than odontogenic tumors, according to non-odontogenic tumors. The most common non-odontogenic tumors in Central giant cell granulomas and ossifying fibromas were granulomas. Ade-nomatoid odontogenic tumor and ameloblastoma were two of the most common odontogenic tumors. Maxillary reconstructions with tem-poralis muscle flap and obturator were quick and effective.

Source link: https://europepmc.org/article/MED/35762625


Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors.

We compared Spitz nevi and melanoma, as well as reference-based and reference-free DNA deconvolution, and investigated the possibility of these techniques in classifying troubled spitzoid tumors by combining detailed genetic and epigenetic study with genetic and epigenetic analysis. Spitz nevi and melanoma were found to cluster independently of nevi and melanoma, displaying a different mutation profile. The methylation in Spitz nevi was comparable to benign nevi, although Leucocytes UnMethylation for Purity in Spitz nevi was similar to melanoma. Spitz tumor cases were grouped between Spitz nevi and melanoma, and according to genetic profile or copy number variations, histologically difficult to classify Spitz tumor cases were determined. Spitz nevi is identified as an independent melanoma unit distinct from both nevi and melanoma by thorough sequencing and methylation analysis.

Source link: https://europepmc.org/article/MED/35737508


Performance of Machine Learning Methods Based on Multi-Sequence Textural Parameters Using Magnetic Resonance Imaging and Clinical Information to Differentiate Malignant and Benign Soft Tissue Tumors.

Rationale and Objectives: Based on textural characteristics of multiparametric magnetic resonance imaging, the aim was to measure the success of a machine learning scheme to distinguish malignant from benign soft tissue tumors. Materials and methods We enrolled 163 patients with soft tissue tumors whose diagnosis was pathologically confirmed. We used Welch's t-test to determine mean signals of all sequences from the malignant and benign tumors. Prediction models were created by a machine learning method using textural elements of each sequence, clinical data, and a single model that incorporates all of the features. The results The diagnostic capabilities of clinical information model were not inferior to the one with textural characteristics of each sequence's sequence. Conclusions: Machine learning techniques based on textural features of mpMRI and clinical data are also effective diagnostic tools for distinguishing between malignant and benign soft tissue tumors.

Source link: https://europepmc.org/article/MED/35725692


Benign Peripheral Non-cranial Nerve Sheath Tumors of the Neck.

Rare lesions, including both schwannomas and neurofibromas, are Benign peripheral nerve sheath tumors. The key nervous systems that are commonly affected include Cervical sympathetic chain, brachial plexus, cervical plexus, and spinal roots and nerves. Intradural and extradural tumors with the shape of Dumbbell are most common in the cervical spine, as well as pure extradural and paravertebral tumors. For growing lesions that are not amenable to surgery, radiotherapy should be considered. For elderly infirm patients who are symptomatic, asymptomatic patients should be monitored and serial scans are a choice.

Source link: https://europepmc.org/article/MED/35689724


Expression pattern and clinical significance of β-catenin gene and protein in patients with primary malignant and benign bone tumors.

Using Real-Time PCR and immunohistochemistry, mRNA expression level and expression of the protein were determined in tumor tissue and peripheral blood mononuclear cells of 150 patients with various types of primary bone tumors. The ubi3b2-catenin expression in malignant bone tumors was highly correlated with tumor grade, length, metastasis, tumor recurrent, and response to chemotherapy. The simultaneous rise in the expression of the u03b2-catenin gene and protein in tumor tissue and in circulating blood cells, as well as its connection with tumor risk points demonstrates the potential role of u03b2-catenin in primary bone tumor pathogenesis.

Source link: https://europepmc.org/article/MED/35676319


Multimodal Approach of Optical Coherence Tomography and Raman Spectroscopy Can Improve Differentiating Benign and Malignant Skin Tumors in Animal Patients.

As in humans, cancer is one of the leading causes of companion animal death. All canine and feline neoplasms have appeared on the skin or directly under it. Up to 30% of all canine and feline neoplasms appear on the skin or directly underneath it. There are only a few published studies that have investigated pet tumors by biophotonics methods. We acquired 1115 optical coherence tomography photos of canine and feline skin, lipomas, soft tissue sarcomas, and mast cell tumors ex vivo, which were later used for automated machine vision analysis. respectively, the combined OCT and Raman findings revealed the most accurate sample differentiation with sensitivities of 0. 968, 1, and 0. 977 for skin, lipomas, and malignant tumors. Based on these findings, we found that the new multimodal strategy, which combined Raman and OCT data, will help distinguish between malignant and benign tissues more precisely.

Source link: https://europepmc.org/article/MED/35740486

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions