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BPPV - Europe PMC

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Last Updated: 24 April 2022

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Effect of ocular fixation on positional nystagmus in BPPV patients.

Objectives The rate of positional nystagmus due to ocular fixation is uncertain. This paper aims to investigate the effect of on the slowed phase velocity of PN during diagnostic manoeuvres with videonystagmography in patients with benign paroxysmal positional vertigo. 58 patients with BPPV were treated, 33 of whom were women, 33 of whom were women, were patients with design DPMs. Several nystagmus before and after OF inception was calculated. If the word x 100/F0 is a character, the rate of PN suppression by OF was discovered in percent. PN during DPMs in BPPV patients is significantly reduced by the FN.

Source link: https://europepmc.org/article/MED/35438599


Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway.

Source: Betahistine is a prescription drug used to treat benign paroxysmal positional vertigo in adults. Methods We treated BPPV patients with Betahistine for four weeks and investigated the clinical stability and expression of CTRP family members in BPPV patients. The expression of CTRP family members, phosphorylation levels of ERK and AKT, and small interfering RNA were found in mice by intratympanic injection, as well as the expression of PPARs. In gentamicin-treated mice and Sloop mutant mice, we also found that Betahistine improved the accuracy of air righting reflex, decreased the time of contact righting reflex, and the scores of head tilt and swimming behaviour in gentamicin-treated mice and Slc26a4 loop/loop mutant mice.

Source link: https://europepmc.org/article/MED/35379352


Current Therapies in Patients With Posterior Semicircular Canal BPPV, a Systematic Review and Network Meta-analysis.

Object: Objective: To determine the effectiveness of various therapies for posterior semicircular canal benign paroxysmal positional vertigo by using current and indirect results from existing randomized studies. Methods Randomized case-control studies that compared the effectiveness of various nonsurgical treatments in PC-BPPV patients at 1 week and 1 month of follow-up were thoroughly investigated. The effect of the Epley maneuver was comparable to that of a sham operation in the pairwise subgroup meta-analysis, but for patients younger than 55 years of age than treatment, the benefit was similar to that of a sham bracelet [rate ratio : 0. 99, 95% confidence interval : 0. 93-1. 05]; for patients with a longer duration before treatment].

Source link: https://europepmc.org/article/MED/34999620

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions