Advanced searches left 3/3

Arsenic - Europe PMC

Summarized by Plex Scholar
Last Updated: 10 August 2022

* If you want to update the article please login/register

WRKY transcription factors: a promising way to deal with arsenic stress in rice.

Rice is always tagged along with rice as rice rises as rice becomes more popular and tends to accumulate it in grains, while rice is always tied to rice. This amassment enables As to enter the food chain that results in unexpected human health risks. Transcription Factors seems to be promising in this field. Here, we explore the possibility of WRKY TFs under As stressed rice as a genetic solution and provide insight into As and rice. Further, we obtain understanding of the WRKY TF gene family and its use in rice. To date, there have been no studies on the role of WRKY TFs under As stressed rice. Low or As free rice cultivars need to be investigated more often so that this gene family can be used as an effective genetic tool that can cause the As cycle to be broken and produce low or As free rice cultivar.

Source link: https://europepmc.org/article/MED/35941412


The association between Arsenic levels and oxidative stress in myocardial infarction: A case-control study

This research was intended to investigate the relationship between the incidence of MI and Arsenic in myocardial infarction patients and healthy people, as well as quantifying the relationship between MI and Ars, total antioxidant capacity, and oxidative stress. Methods This case-control investigation was conducted at Shafa Hospital in Kerman, Iran, among patients with MI and normal people. Based on their angiography findings, patients were divided into two groups, including coronary artery block blocks above 50% and coronary artery blocks less than 50%. In addition, TAC was lower in the CAB > %50 group compared to the CAB's %50 group, and cytotoxic levels for both CAB groups, and no significant differences were found between the two groups. Conclusion Our results show that Ars at 0. 105 ppm has the ability to raise the risk of MI by elevated OS and reduced TAC.

Source link: https://europepmc.org/article/PPR/PPR529369


Minocycline as a Neuroprotective Agent in Arsenic-Induced Neurotoxicity in PC12 Cells.

Humans can be exposed to arsenic by various occupational, medical, or dietetic routes. Both acute and chronic toxicity are likely after arsenic exposure, with severe outcomes in the case. Neurotoxicity is one of the most common signs of arsenic toxicity. The cellular model of this study was the PC12 cell line. Cells were pre-treated with minocycline for 2 h and then incubated for 24 h after adding sodium arsenite. Minocycline not only reduced arsenic-induced cytotoxicity and reduced oxidative stress, but also reduced caspase-8, Bax/Bcl-2, and caspase-3 proteins in comparison to the arsenic-treated cells. Minocycline can effectively shield cells against arsenic-induced neurotoxicity by antioxidant and anti-apoptosis pathways via both intrinsic and extrinsic caspase-dependent apoptotic pathways, so, at this point, it's worth considering it as a promising agent for the treatment of arsenic toxicity by antioxidant and extrinsic caspase-dependent apoptotic pathways; therefore, at this point, it's worth considering it'senic cytosenic cytosol toxicity by antioxidant and anti-induced neurotoxicity by antioxidant and exapoptosenic caspase-depending derivero apoptotic caspase-dependent apoptotic caspase-based cytosenic caspase-based arsenic caspastotic toxicity.

Source link: https://europepmc.org/article/MED/35939230


Identification of arsenic spatial distribution by hydrogeochemical processes represented by different ion ratios in the Hohhot Basin, China.

The Hohhot Basin, China's typical inland basin of the Yellow River Basin, has high amounts of arsenic in its shallow groundwater, although the reasons that cause the distribution of high arsenic levels are yet to be determined. In this investigation, a total of 170 samples of shallow groundwater in the Hohhot Basin were collected and water samples with As > 10 bcg/L accounted for 29. 4% of the total. Poor lateral recharge, adequate exchange between cations in the groundwater and the aquifer matrix, and enhanced reduceibility are all typical in the Dahei River alluvial plain, which serves as the groundwater discharge zone.

Source link: https://europepmc.org/article/MED/35932348


Simultaneous stabilization/solidification of arsenic in acidic wastewater and tin mine tailings with synthetic multiple solid waste base geopolymer.

Stabilization/Solidification is regarded as a viable option for the treatment of arsenic in acidic wastewater and tin mine tailings; however, high cost, high carbon footprint, and stringent reaction requirements are the main drawbacks; however, strict reaction conditions remain the key limitations. At room temperature, an initial Assay concentration of 3914 mg/L, a NaOH content of 4. 8 percent, and an MK content of 20% reduced the As leaching concentration to 1. 55 mg/L. Increasing initial As concentration and MK content aided in the formation of Ca-As precipitates and C-S-H gels, according to further studies. The leaching process of As was determined by semi-dynamic leaching experiments, as indicated by the semi-dynamic leaching procedure.

Source link: https://europepmc.org/article/MED/35940009


Arsenic Prodrug-Mediated Tumor Microenvironment Modulation Platform for Synergetic Glioblastoma Therapy.

Boronic acid was modified on silver to capture As V under an alkaline condition identified as an arsenate plasmonic complex with a distinct Raman response. The APC can precisely release the captured As V in lysosomal acidic pH that specifically targets TME, resulting in a multimodal therapeutic effect such as GSH depletion and reactive oxygen species production. In addition, GSH activation converts As V and As III, which increases glutathione permutation and superoxide dismutase inhibition, while tumor selective etching of the silver core triggered by endogenous H2 O 2 produces and supplies O 2 to help with hypoxia. Both in vitro and in vivo results point to the APC-based chemotherapy as the first to use site-specific tumor therapy using boronate affinity-based arsenic chemotherapeutics.

Source link: https://europepmc.org/article/MED/35921662


Coupled Aerobic Methane Oxidation and Arsenate Reduction Contributes to Soil-Arsenic Mobilization in Agricultural Fields.

Microbial oxidation of organic compounds by bacteria can lead to arsenic release by reducing soil-associated arsenate to the more mobile form arsenite. Although anaerobic reduction of methane has been shown to reduce arsenate, it's unclear if and to what extent aerobic methane oxidation can play a role in reductive arsenic mobilization. Formate served as the interspecies electron carrier assisting aeMO and arsenate reduction, according to metagenic results and metabolite measurements. Overall, this report reveals a previously overlooked yet critical contribution of aeMO to reductive arsenic mobilization.

Source link: https://europepmc.org/article/MED/35920083


Responses of diversity and arsenic-transforming functional genes of soil microorganisms to arsenic hyperaccumulator (Pteris vittata L.)/pomegranate (Punica granatum L.) intercropping.

However, it is also unknown how As-transforming functional bacteria and dominant bacteria in the rhizosphere of P. vittata affect crop rhizosphere soil's microbial characteristics, as well as how As concentration and speciation change in crop rhizosphere soil under intercropping. In pomegranate rhizosphere soil, this research was designed to investigate the effects of different rhizosphere isolation patterns on the bacterial diversity and the number of As-transforming functional genes. The presence of bacteria in pomegranate's rhizosphere soil increased by 16. 3%, according to the study, and the soil bacterial community structure had significantly changed. As methylation gene in pomegranate rhizosphere soil has dramatically increased by 63. 37 percent. Also, the number of As methylation functional genes in crop rhizosphere soil has significantly increased, reducing the As percentage in crop rhizosphere soil, which could reduce As a result.

Source link: https://europepmc.org/article/MED/35926620

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions