* If you want to update the article please login/register
Arsenic is likely in the drinking water of Urmia village due to the location of Urmia County in Urmia-Dokhtar's volcanic belt. There is no statistically significant difference between the amounts of arsenic in the drinking water of the villages of Urmia County in different seasons. Also, smoking causes a statistically significant difference in the amount of arsenic in smokers' hair and non-smoking men's hair. The possibility of arsenic from the volcanic formations of the area into the drinking water of the villages is very high, which is the explanation for the significant difference in the amount of arsenic in the hair of the case and control villages' residents' hair and control villages, as well as the presence of a high percentage of arsenic in the bottom sediments of Lake Urmia's bottom sediments.
Source link: https://doi.org/10.21203/rs.3.rs-1853598/v1
However, rice intake can also be a significant source of inorganic arsenic exposure, thus requiring a risk/benefit analysis. Through a newly introduced optimisation strategy, densities of vital NE were used to categorize rice types in meeting daily NE goals in achieving daily NE targets in a variety of consumption scenarios. We evaluated the risk of exposure for both low and high rice intake scenarios based on iAs results from these rice varieties. According to our analysis, switching to brown or wild rice could increase the intake of several essential nutrients by up to eight times more than white rice. Our results reveal that brown rice can produce 100% adult DRV for Fe, Mg, Cr, P and Mo, P and Mo, as well as substantial contributions for Zn, Se and K. Using rice intake data from mid- to high-consumption countries, we suggest that the amount of rice determines risk from iAs consumed rather than the type of rice.
Source link: https://doi.org/10.1017/s0007114521004025
Acute motor neuropathy (Brazil-Barr) syndrome is a subtype of Guillain-Barru00e9 syndrome with predominant motor axonal changes and no sensory signs or symptoms. Arsenic is a heavy metal that is toxic in small amounts. Its poisonous effects on the nervous system include a peripheral neuropathy similar to GBS. Arsenic is a common choice for an inconvenient killing weapon. It can be white sugar in appearance and be flavorless and odourless2. Pest control in agriculture and as a cotton desiccant are two examples of other uses. Chemical warfare has employed several forms of arsenic. We present a case of a 39-year-old female refugee with a history of bilateral upper and lower limb distal inability, as shown by the following examples. An axonal neuropathy with persistent partial denervation of EMG was revealed by neurophysiology. We suspect her symptoms may be connected to arsenic poisoning, which was used during the Iraqi-Kurdish civil war3.
Source link: https://doi.org/10.1136/jnnp-2022-abn.129
Arsenic trioxide, a systemic lupus erythematosus and chronic GvHD patients, is a therapeutic agent under clinical trials for the treatment of patients with systemic lupus erythematosus and chronic GvHD. We found that the combination of ATO and CuCl 2 caused a high degree of oxidative stress in HL-60 and A20 cells among the various divalent cations tested. In vivo, a cGvHD mouse model, daily injections of ATO 2. 5 g+ CuCl 2 0. 5 g/g promotes a decrease in lymphocyte proliferation and fibrosis that was comparable to that induced by ATO 5 g/g. This co-treatment could be a significant benefit in human patients to greatly reduce the risk of ATO side effects and optimize ATO treatment in pathologies associated with an increase in oxidative stress.
Source link: https://doi.org/10.3389/fimmu.2022.917739
This review looked at the effects of barely u03b2-glucan and barley extracts on sodium trioxide-induced immunosuppression. In this investigation, fifty-four male albino rats were divided into eight groups, each including six rats. For four weeks, Groups 2u20138 received intraperitoneal injections of As 2 O 3 for daily. According to ATO, rats in groups 3, 4, and 5 were given daily doses of u03b-glucan extracts, 40, 80, and 160 mg/day. While lowering MDA levels in rats' spleen tissue, grecan and barley extracts increased CAT and GPx activity, while lowering MDA values. The IgG and IgM levels in the groups treated with barley u03b2-glucan extract were significantly higher than those in barley u03b2-glucan extract groups treated with barley extract. Our results show that barley extracts and barely u03b2-glucan extracts can be used as a component of functional foods to increase immunity.
Source link: https://doi.org/10.21203/rs.3.rs-1781800/v1
Disposing arsenic-bearing waste or minerals over time may lead to arsenic leaking into the groundwater, soil, and then the food chain. This research compares the stability and intrinsic leaching characteristics of smelter high-arsenic flue dust made by cement encapsulation and glass vitrification, as well as specifies if they meet or exceed the requirement for landfill disposition under a variety of environmental relevant conditions. In three arsenic-cement and arsenic-glass samples, toxicity determination leaching procedure, synthetic precipitation leaching process, and Australian standard in short-term and mass transfer from monolithic material using a semi-dynamic leaching tank were used to determine arsenic immobility characteristic in three arsenic-glass and arsenic-glass samples. The method 1315 results revealed that cement encapsulation is not the most effective method for landfilling arsenic waste due to the high arsenic and calcium release over time with alkaline pH.
Source link: https://doi.org/10.3390/min12080939
One way to minimize human exposure to arsenic is limited translocation of arsenic from polluted soil to plant biomass. The findings revealed shoot growth, root growth, and total chlorophyll content of P. purpureum cv. Only the root-to-shoot ratio of plants grown in arsenic-spiked soil was higher than that of non-spiked soil. Plant growth was not stimulated by both soil conditions, even under exogenous plant growth regulator application of each formula. When the first arsenic accumulation in plant roots was discovered, the most effective plant growth regulator was indole butyric acid + calcium chloride. P. purpureum cv cultivation should be grown using 0. 001 mM indole butyric acid + 20 mM calcium chloride. Since it could limit the amount of arsenic entering the food chain, Mott is a forage crop in areas with low arsenic contamination.
Source link: https://doi.org/10.47836/pjtas.45.3.18
The molecular mechanisms that control arsenic-induced bladder carcinogenesis remain unclear. For the malignant transformation of normal bladder epithelial cells, we used a physiological source of NaAsO2 that was exposed for more than a year. Since arsenic exposure from 4 months to 3, we observed an increase in the proliferation and colony-forming capacities of arsenic-exposed cells. Overall, the results indicated that stem cell activators may play a significant role in enabling the arsenic-exposed cells to gain a survival advantage, allowing the healthy epithelial cells to re-programm into a cancer stem cell phenotype, resulting in malignant transformation.
Source link: https://doi.org/10.3390/cells11152435
Methods This case-control study was conducted among patients with MI and healthy people at Shafa Hospital in Kerman, Iran. Patients were divided into two groups, including coronary artery block blocks greater than 50% and coronary artery blocks less than half of the CAB's %50 group, and cytotoxic levels for both CAB and cytotoxic groups, with no significant differences observed between the two groups.
Source link: https://doi.org/10.21203/rs.3.rs-1924941/v1
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions