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"This contribution discusses the findings of uncontrolled longitudinal study looking at the effects of a Multi-Family Therapy as an anti-adolescent Anorexia Nervosa therapy as well as the role of perceived family involvement in these effects. " BMI, eating disorders symptomatology, and perceived family functioning all increased over the course of MFT, and these benefits stayed at both times of follow-up. "Ultimately, we found that the improvement of several aspects of symptomatology aided in the increase of several aspects of symptomatology. ".
Source link: https://doi.org/10.1080/10640266.2022.2069315
"Impaired cognitive flexibility has been cited as a risk factor in the development of anorexia nervosa. " The new survey sought to 1 investigate cognitive flexibility in people at various stages of risk of AN; and 2 compare people with a history of AN to people with varying degrees of risk of AN in cognitive flexibility. Participants completed the Depression Anxiety Stress Scale short-form, the Depression Anxiety Examiner, the Neuroticism Scale, and the Cognitive Flexibility Inventory and neurocognitive the Trail Making Test and the Wisconsin Card Sorting Test online to determine eating disorder indicators, anxiety, and cognitive flexibility. Although high-risk participants self-reported significantly less cognitive skills than those who were not risk groups, the cognitive skills assessment findings were similar across organizations. People at a high risk of AN may have reduced cognitive flexibility than those at a lower risk of AN. ".
Source link: https://doi.org/10.1016/j.jpsychires.2022.05.043
"Empirical evidence and clinical findings point to a strong yet under an acknowledged link between anorexia nervosa and non-suicidal self-injurious conduct. " Three research methods for investigating the relationship between AN and NSSI that integrate psychopathology and neurobiology from the perspective of self-destructiveness: a nosographical approach, a research domain analysis, and a network analysis approach. We conclude that self-destructiveness is a new, DSM-5-transcending concept or psychopathological entity that is reward-driven, and that both AN and NSSI can be characterized as disorders of self-destructiveness.
Source link: https://doi.org/10.3389/fpsyt.2022.756238
"Some oxidative stress parameters have not been investigated in anorexia nervosa patients before," one of which included the gut microbiota-derived metabolite trimethylamine N-oxide and polyphenols, was not investigated. " In serum samples of 20 patients with AN compared to 20 healthy controls, we compared oxidized LDL, total peroxide capacity, endogenous peroxidation capability, endogenous peroxidase activity, and antibodies against oxidized LDL in serum samples of 20 patients with AN in this cross-sectional pilot study.
Source link: https://doi.org/10.3390/antiox11050842
In the context of changed attachment, patients and their relatives share alexithymia, anxiety, depression, and other psychological signs. " We set out to report a sample of Italian families with a child affected by AN, notably including siblings; investigate connections between assessed constructs in patients and their siblings; and investigate potential intergenerational effects. In most participants, parental bonding was found to be suboptimal, but no clear connection was found between specific parenting styles and other measurable characteristics, nor was there any other relevant intergenerational relationship. Any family members face psychological difficulties as a result of Anorexia nervosa.
Source link: https://doi.org/10.3390/bs12050123
"Anorexia nervosa and obsessive disorder" — a neuropsychological profile characterized by elasticity in set-shifting problems and strong detail attention. Both AN and OCD, however, cognitive flexibility may impede treatment acceptance and help explain suboptimal treatment outcomes. This is the first report to compare clinical AN and OCD groups in order to find similarities and differences in cognitive flexibility.
Source link: https://doi.org/10.3389/fpsyt.2022.868921
"Background: Although new studies have reviewed the use of low-dose olanzapine in a variety of health-related disorders, only one research has reviewed the therapy in 13 girls with anorexia nervosa. " Methods: A non-targeted observational naturalistic case-control research aimed at revealing the use and tolerability of low-dose olanzapine in the context of a multidisciplinary hospital intervention for adolescents with AN. Group 1 was treated with low-dose olanzapine, group 2 with full-dose olanzapine, and group 3 was treated without antipsychotics. Depression subtest, survey, and Self-administered Psychiatric Scales for Children and Adolescents were evaluated at admission and discharge with Eating Disorders Inventory-3 Eating Disorders Risk, Body Uneasiness Test Beck's Depression Inventory-III, Beck's Depression Inventory-III and Self-administered Psychiatric Scales for Children and Adolescents. Low-dose olanzapine was well tolerated and used for a mean of 132. 1 days, starting with a dose of 3. 4 mg/day and rising to a maximum dose of 4. 4 mg/day. ".
Source link: https://doi.org/10.1089/cap.2022.0003
"Anorexia nervosa is a psychiatric disorder that can result in cardiac arrests. " As an early marker of myocardial damage, the aim of this research was to investigate global and regional longitudinal strain changes in patients affected by AN as an early indicator of myocardial damage. Patients with AN were more likely of pericardial effusion, smaller left ventricular mass, a lower absolute value of GLS, and basal LS than healthy controls. In 18 of 48 patients with AN compared to 1 of 44 controls, the bull's eye mapping revealed a pattern with blue basal areas in 18 of 48 patients with AN. None of 13 patients with blue areas in the first bull's eye mapping recovered completely, and of 20 patients with a red bull's eye at the first examination, none presented blue areas at the second one. ".
Source link: https://doi.org/10.1016/j.amjcard.2022.03.061
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