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Angina - Wiley Online Library

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Last Updated: 10 March 2022

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Prevention of epicardial coronary artery spasm with intracoronary nitroglycerine during acetylcholine testing in a female patient with resting angina—implications for optimal pharmacological management

Epicardial spasm of the left anterior descending coronary artery and focal spasm of the left circumflex coronary artery can be resolved by intracoronary administration of 0. 2 mg nitroglycerine. After NTG injection, ACh provocation testing was repeated to determine the potential protective effects of NTG. In this patient, there was no more epicardial spasm, indicating that NTG had a protective antispastic effect on the epicardial arteries. Patients with angina due to coronary artery spasm can be difficult to monitor, as pharmacologic drugs are often prescribed on a trial and error basis. We report in this case that we present a novel route toward a more personalized pharmaceutical therapy in coronary artery spasm using a new protocol for invasive coronary spasm testing, which may avoid ineffective treatment trials in such patients.

Source link: https://onlinelibrary.wiley.com/doi/10.1002/ccr3.5480

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions