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Anemia, Megaloblastic - Wiley Online Library

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Last Updated: 02 April 2022

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How I investigate acquired megaloblastic anemia

This essay will explore MA in blood and bone marrow's classic and unique characteristics. Acquired MA is a benign condition for those, but it can be detrimental to some. Vitamin B12 deficiency delay may lead to significant neurologic sequelae that may not fully resolve with therapy, particularly in neonates and young infants. The blood and bone marrow functions in MA can closely mimic thrombocytopenic purpura, myelodysplasia, and other myeloid neoplasms. Both pancytopenia and normal MCV at presentation are common in MA and pose unique challenges for the diagnostician. The MA partially treated MA is also a significant diagnostic "trap. " MA is a highly responsive to medical care, and patients tend to recover quickly after treatment begins. However, the extensive combination of medical and hematologic features makes diagnosis of MA a new challenge for the hematopathologist.

Source link: https://onlinelibrary.wiley.com/doi/10.1111/ijlh.13789

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions