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Anabolic Steroids - PubMed

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Last Updated: 01 July 2022

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ADHD symptoms and use of anabolic androgenic steroids among male weightlifters.

We wanted to see if AAS use in male weightlifters was related to ADHD symptoms, as well as the correlation between ADHD symptoms and cognitive health. Self-reported ADHD symptoms were significantly higher among AAS users compared to WLC, with scores in the range indicating clinically relevant ADHD was significantly more common in the AAS-using population. The age of initiation of AAS usage was inversely correlated with ADHD scale scores. Recognising a connection between ADHD symptoms and AAS use may help with drug avoidance efforts in sports.

Source link: https://doi.org/10.1038/s41598-022-12977-w


Medaka embryos as a model for metabolism of anabolic steroids.

We looked at whether Oryzias latipes embryos could be an alternative, non-animal test model to study human-like metabolism in the present study. We exposed medaka embryos at the morula stage to the anabolic steroid metandienone for a period of 2 to 8 days in the present study. We determined the embryos' developmental status according to the fish embryo toxicity test. The exposition to 50 b5M metandienone was found, but a significant rise of the heart beat was also present in those people exposed to the lower dose for 8 days.

Source link: https://doi.org/10.1007/s00204-022-03284-4


No association between psychiatric symptoms and doses of anabolic steroids in a cohort of male and female bodybuilders.

This report confirmed the use of AAS in a cohort of 103 bodybuilders using WADA's steroid profile of suspicious use of AAS, urinary detection of AAS, and measurement of sexual hormones. About one-third of participants received scores on the HAM-A anxiety scale, which is equivalent to moderate to severe symptoms of anxiety. The majority of participants of the BRIEF-TEMPS scale displayed hyperthymic temperament. No significant difference was found between males and females in the presence of psychiatric signs, and there was no correlation between psychiatric signs and estimated weekly doses of AAS. Scores on the BPQ scale were compared to those on the time of AAS use, indicating a negative correlation. We investigate the differences in AAS use between male and female bodybuilders and AAS screening in the general population. Our results support the importance of mental wellbeing among individuals using AAS.

Source link: https://doi.org/10.1002/dta.3230

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions