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Amino Acid - DOAJ

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Last Updated: 10 May 2022

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Corrosion Inhibition of Aluminium in Acidic Medium using Amino Acid (Methionine)

paramol. Aluminiumm's corrosion behavior in corrosion is shown by 0. 6 mol. In the absence and presence of different amounts of amino acid, methionine, as an environmentally friendly corrosion inhibitor over temperature range K, the inhibition efficiency increased with an increase in inhibitor concentrations but decreased as temperature increased.

Source link: https://doaj.org/article/43c9dd559734444cb4c6b58055ca3e46


Synthesis and antibacterial study of the ligand type Schiff base derived from amino acid [L- Phenylalanine] and its complexes with Co (II), Ni (II), Cu (II) and Zn (II) ions

To give the Schiff base sodium 2--3-phenylpropanoate, which was used as a precursor [NaHL]], the L-Phenylalanine amino acid was condensed with 2-hydroxybezaldehyde [NaHL]. [FTIR, UV-Vis, atomic absorption], melting point, chloride content, conductivity, and magnetic susceptibility measurements were all used to describe the Na2L ligand and All complexes, as well as the Na2L ligand, which was characterized by 1H NMR.

Source link: https://doaj.org/article/54057a3cf19c4605a41151acf3ad0058


Automated Reconstruction and Manual Curation of Amino Acid Biosynthesis Pathways in Sulfolobus solfataricus P2

The Crenarchaeon Sulfataricus P2 genome has greatly increased the number of genomes that are now available, including the Crenarchaeon Sulfataricus P2 genome. The genome-scale metabolic pathways in Sulfolobus solfataricus P2 were predicted by implementing the 'Pathway Tools' software in Sulfolobus solfataricus P2 as a reference knowledge base, according to the MetaCyc database. Sulfolobus solfataricus P2 was the first of a Pathway/Genome Data Base. Many amino acid biosynthetic metabolic pathways were able to be predicted by the "PathoLogic" component of the "Pathway Tools" program. To the Pathway/Genome data base of Sulfolobus solfataricus P2's Pathway/Genome data base, a variety of Amino acid biosynthesis and Alanine biosynthesis, as well as the superpathway of Phenylalanine, Tyrosine, and Tryptophan biosynthesis variation II were added to the Pathway/Genome path. Molecular pathway reconstructions of closely related Bacteria and Archaea can be used with genomic annotations and metabolic pathway reconstructions in Sulfolobus solfataricus P2's PGDB.

Source link: https://doi.org/10.30526/32.3.2271


Plasma and Whole Blood Taurine Concentrations in Dogs May Not Be Sensitive Indicators of Taurine Deficiency When Dietary Sulfur Amino Acid Content Is Reduced

In large dogs and small dogs, the lowest SAA diet, 3. 4 methionine, and 2. 9% cystine, taurine concentrations were not different between groups, although taurine in plasma declined in large but not in small dogs, and in small dogs, by 56%. In large than small dogs, taurine and fecal bile acids were lower and fecal bile acids were higher. ConclusionsBlood taurine depletion in dogs caused by a lack of bioavailable SAA in dogs, especially in large dogs, could not be a reliable predictor of taurine depletion caused by inadequate intake of taurine in dogs. Taurine status and nutritional SAA requirements of dogs can significantly depend on taurine loss caused by intestinal microbiota.

Source link: https://doi.org/10.3389/fvets.2022.873460


Using amino acid features to identify the pathogenicity of influenza B virus

Influenza B virus can cause epidemics with high pathogenicity, posing a significant threat to public health. Methods The study included all 11 influenza virus proteins encoded in eight genome segments of 1724 strains. From 67 feature descriptors and input to the random forest classifier, to output descriptive information about the class name and probabilistic forecast, to product descriptive information about the class label and probabilistic prediction. Mutations at position 135 of the hemagglutinin protein had the highest entropy value, with mutations at position 135 of the hemagglutinin protein displaying the highest entropy value. The optimal probabilistic features had a maximum accuracy of 94. 2% and a maximum Matthews correlation coefficient of 88. 4%, while the optimal probabilistic features had a maximum error rate of 94. 9% and a maximum Matthews correlation coefficient of 88. 2%, with a maximum Matthews correlation coefficient of 88. 2%. The sequential forward search strategy had a better success than the classical ensemble method.

Source link: https://doi.org/10.1186/s40249-022-00974-0


Phylogenies from unaligned proteomes using sequence environments of amino acid residues

We herein introduce a new approach based on the species-specific amino acid neighborhood preferences. In the context of vector spaces, these divergent preferences can be assessed. Moreover, we have evidence that the new strategy can be used safely on datasets generated by non-orthologous protein sequences, implying that the procedure does not only does not exclude orthologous proteins' identification, but also does not specify their presence in the collected dataset. These findings reveal that amino acids' neighborhood preference, which may be of great use in phylogenomics, gives a phylogenetic signal that may be of great use in phylogenomics.

Source link: https://doi.org/10.1038/s41598-022-11370-x


Relationship between dietary amino acid release kinetics and nitrogen deposition in growing pigs

Although the protein content of swine diets is based on the ileal digestibility of protein and amino acids under new nutrition standards, the nitrogen utilization of swine depends on protein source, which may be related to AA release kinetics. In this study, a 2 factorial system with casein-enriched or corn gluten meal -enriched protein sources at different digestible crude protein levels was applied to 24 crossbred growing pigs in four experiments to determine the effects of AA release kinetics on nitrogen deposition in growing pigs. The results revealed that the time of AA peak in the CGM diet was 12 h later than that in the CAS diet. The N. CGM had the poorest AA release synchronism among the four diets, but the N. CAS had the greatest among the four diets.

Source link: https://doi.org/10.1016/j.aninu.2022.01.001


An amino acid-defined diet impairs tumour growth in mice by promoting endoplasmic reticulum stress and mTOR inhibition

Moreover, we investigated the dietary, biochemical, and molecular effects of two mixtures that mimic the SFA-EAA diet and SFA-CAA diet in numerous cancer and non-cancer cells. SFA-EAA diet reduced tumour formation in vivo, stimulated endoplasmic reticulum stress, and stifled mechanistic/mammalian targets of rapamycin synthesis in tumors. According to the EAAm, but not the CAAm, causes apoptotic cell death in cancer cells without directly impacting cancer cell survival and proliferation. EAAm has a branched-chain amino acid oxidation and reduced glycolysis, ATP production, redox potential, and intracellular presence of specific non-essential amino acids in cancer cells. Conclusion: These results add up to specific cancer cell lines' death, and they also show that modification of dietary EAA composition and profile can be a useful complement to standard chemotherapy for specific cancers.

Source link: https://doi.org/10.1016/j.molmet.2022.101478


Strategies to transform remote C(sp3)-H bonds of amino acid derivatives

Although, a variety of techniques for specific reactions in the proximal - or -C-H bond exist, selective functionalization of distal bonds in amino acids remains a challenge. Transition metal catalyzed C–H functionalization has emerged as a key tool for C–H bond conversions in recent years. We hope to give the reader a complete summary of the state of art in the use of site-specific C–H functionalization techniques for the conversion of distal C–H bonds of amino acids and peptides.

Source link: https://doi.org/10.1016/j.tchem.2022.100005


Unnatural Amino Acid: 4-Aminopyrazolonyl Amino Acid Comprising Tri-Peptides Forms Organogel With Co-Solvent (EtOAc:Hexane)

Ampyrone's chemical crystal structure has been shown to have excellent hydrogen bonding locations and can be used as the prospective scaffold of supramolecular self-assembly. This molecule has been converted into unnatural amino acids like aminopyrazolone amino acid and its peptides recently. Organogel is created by sonication at 50–55 degrees Celsius with 0. 7 percent in ethyl acetate, hexane. This paper reveals that one of its amino acids, O-alkylated ampyrone, containing hybrid peptides, is the product of organogel.

Source link: https://doi.org/10.3389/fchem.2022.821971

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions