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Atopic dermatitis is a skin disorder that is characterized by skin inflammation. Dry, itchy skin, and red rashes that appear and disappear are among the signs of atopic dermatitis. The rashes are common in children, and they are usually found in the elbows and knees along the front of the neck. Scratching the itchy skin can result in oozing and crusting of the rashes, as well as skin thickening and hardening. Although atopic dermatitis is not triggered by an allergic reaction, it is also linked to other autoimmune disorders: up to 60% of people with atopic dermatitis have asthma or hay fever later in life, and up to 30% have food allergies. However, not all individuals with atopic dermatitis will progress through the atopic march, and not all people with one allergic disorder will progress to others. " Individuals with atopic dermatitis are at an elevated risk of acquiring other conditions relating to inflammation, such as inflammatory bowel disease, rheumatoid arthritis, and hair loss as a result of a malfunctioning immune response. In a select group of people with atopic dermatitis, the immune system is unable to shield the body from foreign invaders such as bacteria and fungi. Atopic dermatitis can also be a feature of distinct disorders that have a variety of signs and symptoms, such as skin abnormalities and immunodeficiency.
Asthma is a respiratory disease that is characterized by inflammation of the airways and repeated episodes of respiratory difficulties. When allergen-containing chemicals are inhaled, asthmatics sufferers are allergic to allergic asthma, causing an allergic reaction. Allergens are harmless substances that the body's immune system mistakenly responds to as if they are harmful. An asthma attack is characterized by tightening of the muscles around the airways, which narrows the airway and makes breathing difficult. Some people with allergic asthma have another autoimmune condition, such as hay fever or food allergies. Asthma is often part of a series of allergic disorders, referred to as the atopic march. However, not all asthma sufferers have progressed through the atopic march, and not all people with one allergic disease will have the same asthma symptoms.
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