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Allergic Rhinitis - DOAJ

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Last Updated: 04 August 2022

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Early childhood traffic-related air pollution and risk of allergic rhinitis at 2–4 years of age modification by family stress and male gender: a case-control study in Shenyang, China

Abstract Background Briefing Abstract Background Few studies have looked at the impact of family stress and male gender on the association between early exposure to traffic-related air pollution and preschool children's allergic rhinitis risk. According to the increase of the interquartile range in the exposure range, we used logistic regression model to measure the odds ratio and 95% confidence interval for childhood AR with exposure to various air pollutants. Findings The incidence of AR in children aged 2 -20134 years was attributed to early TRAP exposure. PM10 and NO2 were positively correlated to AR symptoms among children with family stress and boys. Among children without family tension and girls, no such link was found. Conclusions Family tensions and masculinity may raise the risk of AR in preschool children with early exposure to PM10 and NO2.

Source link: https://doi.org/10.1186/s12199-021-00969-7


An anti-inflammatory and anti-fibrotic proprietary Chinese medicine nasal spray designated as Allergic Rhinitis Nose Drops (ARND) with potential to prevent SARS-CoV-2 coronavirus infection by targeting RBD (Delta)- angiotensin converting enzyme 2 (ACE2) binding

Abstract Background: Since the COVID-19 outbreak has resulted in over 313,000,000 confirmed cases of disease and over 5,500,000 deaths, extensive research has been carried out to find agents/ vaccines against COVID-19. An increasing number of direct evidence based on clinical trials of traditional Chinese medications in the treatment of COVID-19 has been reported. An in vitro pseudovirus assay determined the inhibitory effect of ARND on viral infection. Conclusions The findings revealed that ARND not only reduced pseudovirus infection and undermined the Spike protein's binding affinity, but also slowed the immune response after infection, which may lead to a more effective prognosis with a reduced risk of pulmonary fibrosis. In vivo and COVID-19 patients, the results show both the conceptual framework for further research into ARND as an antiviral hygienic drug and further research into ARND in the live virus.

Source link: https://doi.org/10.1186/s13020-022-00635-2


Assessment of knowledge, attitude, and practice of community pharmacists towards allergic rhinitis and its management in Khartoum state: A cross-sectional survey

Allergic rhinitis is a common disease that has elevated in incidence in recent decades. Since many medications are available over the counter, pharmacists are often the first-line contact. In Khartoum state, a cross-sectional study was conducted using a validated self-administered questionnaire. The age group 25 to 30 years was more than half 196 in the United States. Pharmacists have a poor level of experience in terms of symptoms of AR, classification, features of various classes of AR, pregnancy categories of drugs used in the management of AR, appropriate inhaler technique usage, and different classes of medications. Pharmacists with a poor attitude toward their role in AR, diagnosis of AR, and inhalation device education are among pharmacists' education.

Source link: https://doi.org/10.1016/j.imu.2022.101020


Mometasone Furoate in Non-Allergic Rhinitis: A Real-Life Italian Study

Background: A real-life, observational, prospective study is conducted in order to determine the effectiveness of intranasal mometasone furoate in patients with non-allergic rhinitis. Conclusions: The findings of this research show that intranasal mometasone furoate is a safe treatment for patients with NAR.

Source link: https://doi.org/10.3390/jpm12071179


Impact of Preventive Measures on Subjective Symptoms and Antigen Sensitization against Japanese Cedar, Cypress Pollen and House Dust Mites in Patients with Allergic Rhinitis: A Retrospective Analysis in the COVID-19 Era

We investigated whether these preventive habits had an effect on the incidence and severity of allergy sensitization against pollen and household dust antigens in patients with allergic rhinitis. In the COVID period, the positive rates for Japanese cedar and cypress in the 40u201359-year-olds and those for house dust in the 20u201339-year-olds were considerably reduced compared to those in the pre-COVID period. According to our analysis of the patients' u2019 medical results, 46. 5 percent of the pollinosis patients reported improvement in nasal symptoms after the three seasons of pollen dispersion in the COVID period.

Source link: https://doi.org/10.3390/atmos13071000


Efficacy of Diethylcarbamazine in Allergic Rhinitis as an Adjuvant to Antihistamines : A Comparative Study

Detailed information: Allergic rhinitis is a form of asthma in the nose that occurs when the immune system overreacts to allergens in the air. People with allergic rhinitis may have asthma, allergic conjunctivitis, or atopic dermatitis. When adding to the antihistaminic treatment, the aim is to determine the sensitivity of allergic rhinitis in patients with allergic rhinitis. Methods: This is a single blind randomized control trial involving 50 allergic rhinitis patients aged 13-60 years as patients and 50 as controls in a single blind controlled trial. For a period of 21 days, the patients were given Tablet Diethyl carbamazine 300mg and Tablet cetrizine 10 mg. Out of 50 patients in the study cohort, 20 cases showed change, 30 cases did not, and 30 cases did not show any change; out of 50 controls, 6 showed advancement, and 44 didn't show any change; and 44 didn't show any change;.

Source link: https://doi.org/10.18502/jpc.v10i2.9979


Prevalence of psychological stress in allergic rhinitis patients attending a tertiary care hospital - A cross sectional study

Allergic Rhinitis is a common symptom in patients attending the Otorhinolaryngology department, according to the anthropology department. Objective: To determine the prevalence of psychological distress in AR patients and determine its connection to the duration and severity of the disease. This is a cross-sectional review of AR patients receiving ENT OPD for the first 6 months. AR patients were diagnosed and classified as per ARIA guidelines and categorized as per ARIA guidelines. Using the Persuaded Stress Scale, then and the participants were subjected to a standard psychiatric interview and their psychological distress were measured. Results: Of 1804 new patients attending ENT OPD, 58 were diagnosed with AR. Among AR patients, those with a persistent moderate-severe type were discovered to have a high prevalence rate, which is statistically significant. In AR patients, there is no correlation between the severity of symptoms and duration of illness to significant psychological stress. Patients with AR have significant psychological difficulties, which should not be ignored during therapy.

Source link: https://doi.org/10.4103/2321-7006.302674


A comparative study of nasal smear eosinophilia vs absolute eosinophilic count in patients with allergic rhinitis

Despite ENT OPD, Allergic rhinitis is one of the most common chronic diseases that affect patients with ENT OPD. A. R. is an A. R. diagnostic instrument that can be used to determine Nasal Smear Eosinophilia's value with Absolute Eosinophilic Count of peripheral blood as a diagnostic test and develop a diagnostic tool for A. R. There were 36 patients in the study group, and 14 patients served as controls. As diagnostic results were established, allergic rhinitis was diagnosed as per standard criteria and sensitivity and specificity of NSE and AEC. Conclusion: Nasal Smear Eosinophilic Count can be used as a simple, cost-effective, and semi-invasive diagnostic test for A. R in the peripheral setting.

Source link: https://doi.org/10.4103/2321-7006.301955


CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses

Allergic rhinitis is an immunoglobulin E-mediated type 2 inflammation of the nasal mucosa that is mainly triggered by type 2 helper T cells and type 2 innate lymphoid cells. Using global and CD4+ T cell-specific Cd226 knockout mice, this research is aimed at clarifying the role of CD226 in allergic inflammatory responses in murine AR murine AR. The results revealed that global Cd226 KO mice, but not CD4+ T cell-specific Cd226 KO mice, had attenuated AR nasal symptoms, but not CD4+ T cell-specific Cd226 KO mice. After ovalbumin stimulation, ILC2s in the murine nasal mucosa showed higher amounts of CD226 after ovalbumin stimulation, and CD226 deficiency resulted in a decrease in the proportion of nasal ILC2s and ILC2-related inflammatory gene expression. Hence, the effect of CD226 on the AR mouse model may have to do with the regulation of ILC2 function rather than CD4+ T cells.

Source link: https://doi.org/10.1155/2022/1756395


Effectiveness and safety of allergen immunotherapy in patients with allergic rhinitis complicated by rheumatic autoimmune diseases: a case series study

Abstract Summary of Allergen immunotherapy is the only therapy that has changed allergic disease's natural history. There have been no long-term reports of patients with AIT receiving AIT, so the effectiveness and safety of AIT in these patients are uncertain. Patients with allergic rhinitis at our hospital were chosen by AIT for allergic rhinitis. Changes in the performance of RAD patients were monitored for two years from baseline, including those who stopped AIT. The majority of the adverse events related to AIT were mild, in which only one patient required medical intervention due to worsening rhinitis symptoms. In the second year of therapy, AIT's eye and nasal symptom scores increased from 1. 67 at baseline to 0. 67 in the nine patients who were able to continue AIT. AIT is a safe and effective treatment methodology for patients with allergic rhinitis complicated by RADs.

Source link: https://doi.org/10.1186/s13223-022-00703-0

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions