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Allergen - Springer Nature

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Last Updated: 28 January 2023

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High pan-allergen content in mango and peach in Taiwan

Background Many plant food allergens have been implicated in cross-reactivities and can result in repetitive pan-allergenic exposures, which may exacerbate patientsu2019 allergic symptoms. This report was conducted to determine LTP, profilin, and PR-10 in Taiwan's 15 most popular fruits. Among all 15 fruit extracts tested, peach and mango had the highest amounts of profilin, nsLTP, and PR-10. Conclusion The peach and mango are among the 15 common fruits tested for epidemiological evidence, according to epidemiological results.

Source link: https://doi.org/10.1007/s40629-022-00240-7


Allergen bronchoprovocation: correlation between FEV_1 maximal percent fall and area under the FEV_1 curve and impact of allergen on recovery

During allergen bronchoprovocation testing, house dust mite causes more responses than other allergens. The maximum decrease in forced expiratory volume in one second and the area under the FEV_1 vs time curve are the most reported results of ABP experiments, according to the two standardized methods for reporting results. Aims We wanted to determine if the EAR recovery period for HDM would be longer than other allergens during the early asthmatic reaction and the late asthmatic response, as well as determining whether the EAR response period for HDM will be longer than other allergens. We compared EAR_ and LAR_1, max, AUC, and absolute difference in FEV_1, max to the most recovered FEV_1. There were no signs of delayed EAR_ restoration following HDM tests, so HDM did not produce a greater response than any of the other allergens tested.

Source link: https://doi.org/10.1186/s13223-023-00759-6


Treatment with pollen allergen immunotherapy improves health-related quality of life in children and adolescents: a three-year follow-up-study

Background The immunological effect of allergen-specific immunotherapy has been well documented, but no studies have looked into the long-term effects of pollen subcutaneous immunotherapy on children and adolescents, as well as adults. In a 3-year follow-up, the aim of this research was to investigate the effect of pollen SCIT on HRQoL and to determine the connection between HRQoL and symptoms in children and adolescents with allergic rhinoconjunctivitis. For the correlation between HRQoL and influencing factors, both ANOVA and t-test were used to determine time, between groups, and a linear mixed model. After one year of SCIT, the proportion of children with severe or invasive symptoms decreased from 35. 6% to 4. 5 percent. After 1 year of pollen SCIT and was maintained during the treatment years, the number of children with severe or moderate symptoms from eyes, Nose, and/or lungs had dramatically decreased.

Source link: https://doi.org/10.1186/s13223-023-00756-9


Identification of Potential Allergens of Atractylodes japonica and Addition of Panels for Allergic Diseases

The use of herbal medicines is on the rise worldwide. The aim of this research is to determine if Atractylodes japonica extract, a natural medicine, binds to human serum IgE and causes an allergic reaction as an immune response disorder complex, as well as providing a panel of allergens to the Allergy Q kit. Using MASCOT program matching, we then used Western blotting and in-gel digest to find proteins that bind to human serum IgE and predicted six proteins, including putative chitinases, proteasomes, and hypothetical proteins.

Source link: https://doi.org/10.1007/s13206-022-00094-9


Steady-state estradiol triggers a unique innate immune response to allergen resulting in increased airway resistance

Rationale Asthma is a persistent airway disease that occurs more frequently in women than men during reproductive years. Long-term use of oral contraceptives has reduced the onset of asthma in women of reproductive age, according to population studies. We found that steady-state estrogen levels could reduce airway inflammation and airway hyperresponsiveness to the methamphetamine challenge in the most recent review. Immunotyping was used to compare inflammatory proteins and immune populations with improved or worse pulmonary outcomes measured by invasive pulmonary mechanics methods. In the remaining lung tissue, although these commonly used allergic cells were reduced in the BAL or airways, we found no changes in neutrophils, CD3+ T cells, or CD19+ B cells. In OVX-EVA-treated mice in the BAL, inflammatory cytokines were also reduced in OVX-E2-OVA-treated animals in comparison to Female-INTACT-OVA mice in the BAL, but in the lung tissue IL-5, IL-13, and IL-33 were similar in OVX-E2-OVA mice and FACT OVA mice. Conclusions The therapy may have a limiting effect on estrogen receptors, ILC2 and possibly other immune populations that may lead to asthma symptoms in those females with perimenstrual asthma deteriorating, but note, that long-term use of estrogens or hormone receptor modulators can be harmful to the lung microenvironment. Neutrophils and CD19+ B cells were unaffected by estrogen therapy in lung tissue tissues.

Source link: https://doi.org/10.1186/s13293-022-00483-7


IgE and IgG4 Epitope Mapping of Food Allergens with a Peptide Microarray Immunoassay

The last one has a special interest in food allergy because the emergence of tolerance to food allergens has been linked to a decrease in IgE and an increase in IgG4 levels against linear epitopes. Recent studies comparing the linear epitopes of food allergens with peptide microarray immunoassays have found peptide biomarkers that can be used to diagnose food allergies in early and determine tolerance severity and self-development. We've worked on epitope mapping of the two most common food allergens in the Spanish population, cowu2019s milk, and chicken eggs, using this strategy. This chapter describes the procedure used to create microarrays using a collection of overlapping peptides corresponding to the main sequences of food allergens and data processing and analysis of IgE and IgG4 binding epitopes.

Source link: https://doi.org/10.1007/978-1-0716-2732-7_16


Relevance of Typographic Factors in the Identification of Allergens in Food Labels

The mandatory declaration of the 14 most common food allergens in all food products containers is clearer legislation for the mandatory notification of the 14 most common food allergens in all food products packagings. Despite this, shoppers with food allergies continue to have trouble understanding the relevant messages for the safe selection of foods for consumption. This research sought to identify the most useful visual cubes for finding and reading food allergen data according to the available online database corpus on labelling in the food decision-making process.

Source link: https://doi.org/10.1007/978-3-031-20364-0_62

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions