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Air Pollution - ClinicalTrials.gov

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Last Updated: 08 July 2022

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Household Air Pollution and Health: A Multi-country LPG Intervention Trial

The resulting household air pollution is the third leading risk factor in the 2010 global burden of disease, accounting for an estimated 4. 3 million deaths annually, many among women and young children. There have been no field trials with liquefied petroleum cookstoves, perhaps the most cost-effective measure. The aim of this research was to conduct a randomized controlled trial of LPG stove and fuel distribution in 3,200 households in four LMICs to produce rigorous evidence regarding potential health benefits throughout the lifespan. Each intervention site will randomly assign half of their households LPG stoves and an 18-month supply of LPG. The mother will be followed along with her child until she children's age is 1 year old. The researchers will also enroll and follow her during the 18-month follow-up period in order to determine cardiopulmonary, metabolic, and cancer outcomes in households with a second, non-pregnant older adult woman. This report will assess cookstove use, perform repeated personal exposure assessments to HAP, and gather dried blood spots and urine samples for biomarker analysis and biospecimen storage on all participants at various time points. This report will examine the following objectives: using an intent-to-treat approach, identify the effects of a random LPG stove and fuel intervention in four diverse LMIC populations using a common protocol; determine the impact of a randomized LPG stove and fuel intervention on health in four diverse LMIC populations using a single protocol; and identify correlations between LPG intervention and several key environmental and exploratory biomarkers of exposure/health outcomes.

Source link: https://clinicaltrials.gov/ct2/show/NCT02944682

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions