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Aerobic Exercise - Astrophysics Data System

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Last Updated: 16 May 2022

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Aerobic exercise promotes the expression of ATGL and attenuates inflammation to improve hepatic steatosis via lncRNA SRA

It has long been known that aerobic exercise aids in preventing and improving non-alcoholic fatty liver. However, it is also unknown if aerobic exercise can prevent and treat hepatic lipid accumulation via SRA. The mice were randomly divided into four groups as follows: normal control group, ordinary aerobic exercise group, high-fat diet group, and high-fat diet plus aerobic exercise group were randomly divided into four groups, as follows: normal control group, normal aerobic exercise group, high-fat diet group, and high-fat diet plus aerobic exercise group. In the HAE group, body weight, as well as blood TC, LDL-C, and liver TG were significantly lower than in the HFD group than in the HFD group.

Source link: https://ui.adsabs.harvard.edu/abs/2022NatSR..12.5370W/abstract


Aerobic exercise improves LPS-induced sepsis via regulating the Warburg effect in mice

Induction of sepsis, mice receiving 5 mg/kg LPS and Ex + LPS were intraperitoneally administered sepsis. This review investigated the effects of AE on systemic inflammation, lung permeability, and bronchoalveolar fibrous fluid cell count, oxidative stress-related variables, plasma glucose levels, serum insulin levels, plasma glucose level, and plasma high-mobility group box 1 results, as well as nuclear factor erythroid 2-related factor 2 mRNA expression levels in lung tissue. Neuophil content in organs has been reduced by AE by a large amount. During sepsis, AE reduced the serum levels of lactate and HMGB1, but serum glucose levels and serum insulin levels increased. AE impairs LPS-induced lactate and HMGB1 for a portion because AE elevates serum insulin levels and reduces the amounts of Glut1. AE is a novel therapeutic approach for sepsis affecting aerobic glycolysis.

Source link: https://ui.adsabs.harvard.edu/abs/2021NatSR..1117772W/abstract

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions