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Adjunct Treatment - PubMed

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Last Updated: 20 September 2022

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Comparison of Ozonated Olive Oil and Chlorhexidine Gel as an Adjunct to Nonsurgical Periodontal Therapy for the Treatment of Chronic Periodontitis: A Randomized Controlled Clinical Trial.

The ultimate aim of any periodontal therapy is complete elimination of the pathogenic microorganisms from the gingival sulcus region. Although Chlorhexidine is the gold standard as an antiplaque agent, it has suffered a number of drawbacks. Therefore, the purpose of this research was to determine and compare the effectiveness of local application of CHX and ozonated olive oil as an adjunct to SRP for chronic periodontitis treatment.

Source link: https://doi.org/10.4103/jpbs.jpbs_565_21


Wearable adjunct ozone and antibiotic therapy system for treatment of Gram-negative dermal bacterial infection.

Through a novel dressing with drug-eluting nanofibers, the device presented here provides one solution to this problem by a wearable therapy that delivers and uses gaseous ozone as an adjunct therapy with topical antibiotics. By using oxidative ozone to remove barriers created by the bacterial cell wall, Gram-negative bacteria's sensitivity to common antibiotics has dramatically increased the sensitivity of Gram-negative bacteria to common antibiotics. The dressing's permeability decreases as a result of decreasing gas permeability, but not inducing decreasing gas permeability. The ozone generation at 4 mg/h was found to be the highest ozone levels for high antimicrobial activity with minimal cytotoxicity, according to a systematic review. Complete eradication of Gram-negative bacteria with ozone and antibiotics that were traditionally used only for Gram-positive bacteria, according to the strength of ozone as an enablerable adjunct treatment option to sensitize bacteria strains to otherwise ineffective antibiotics.

Source link: https://doi.org/10.1038/s41598-022-17495-3


Effects of diode and erbium lasers as an adjunct to scaling and root planing on clinical and immunological parameters in non-surgical periodontal treatment: a split-mouth randomized controlled clinical trial-"effects of lasers on immunological parameters".

The effects of diode and erbium lasers, as an adjunct to scaling and root planning, on clinical and immunological parameters in non-surgical periodontal therapy were analyzed by this study. In this split-mouth controlled clinical trial, 17 participants with at least one periodontically involved tooth in each quadrant received oral hygiene instruction and full-mouth SRP. One random quadrant in each participant received a 940 nm diode laser, while another quadrant received 2780 nm Er,Cr:YSGG laser irradiation. The increase in IL-10 in the erbium group was much greater than that in other groups. With a larger decrease in the MMP-13 level in laser groups, the MMP-13 score was much lower in laser groups, despite the MMP-13's decline in erbium group. Application of 940 nm diode and 2780 nm Er,Cr:YSGG lasers as an adjunct to SRP dramatically reduced the GCF level of MMP-13, with no definite clinical advantage over SRP monotherapy.

Source link: https://doi.org/10.1007/s10103-022-03596-y

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions