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Acid Nucleic Biosensor - Europe PMC

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Last Updated: 12 November 2022

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A nucleic acid dye-enhanced electrochemical biosensor for the label-free detection of Hg 2+ based on a gold nanoparticle-modified disposable screen-printed electrode.

The DNA probe was turned into a hairpin structure where positively charged GelRed molecules were embedded into the double-stranded portion of the hairpin after Hg 2+ was tied with a DNA test by thymine -Hg 2+ mismatch. The peak current of [Fe 6] 3-/4- demonstrated a good linear correlation with lgC Hg 2+ in the concentration of Hg 2+ linear range from 0. 1 nM to 500 nM, and the detection limit was set as 0. 04 nM under optimized experimental conditions, with a good linear relationship. In the meantime, the newly developed electrochemical sensor was used in the analysis of Hg 2+ in tap water and river water samples, ranging from 81. 0 to 114%.

Source link: https://europepmc.org/article/MED/36000503

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions