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Achalasia - Crossref

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Last Updated: 28 July 2022

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Achalasia in the elderly patient: a comparative study

Patients with achalasia have no information about the effect of age on esophageal motility in patients with achalasia. Therefore, as both age and achalasia may produce similar degenerative changes in the intramural myenteric plexus, it is likely that advanced age could play a significant role in raising the clinical and anthropometric abnormalities common to patients with achalasia. P = 0. 001 and chest pain P = 0. 012 than the elderly, among the young patients, had a higher incidence of heartburn P = 0. 001 and chest pain P = 0. 012 than the elderly. CONCLUSION: Elderly patients with achalasia had a lower sphincter pressure than the young, even when we excluded patients from Chagas' disease, but as a group, they were less symptomatic.

Source link: https://doi.org/10.1590/s0004-28032011000100005


LncRNA expression in idiopathic achalasia: New insight and preliminary exploration into pathogenesis

Abstract Idiopathic achalasia is a common esophageal motility disorder characterized by the absence of esophageal peristalsis and poor relaxation of the lower esophageal sphincter. We conducted lncRNA and mRNA microarray analyses to help with the pathogenesis. For microarray, microarray samples from 5 patients and four controls were used. Using cis/trans-regulatory schemes, several novel lncRNA and mRNA were predicted, subsequently followed by the Gene Ontology and KEGG pathway enrichment analysis to determine the biophysical effect, revealing the biophysical effect. The cell adhesion molecule pathway was discovered to be a common route in a biophysical function analysis.

Source link: https://doi.org/10.1515/med-2022-0473


Surgical Treatment of Esophageal Advanced Achalasia

The esophagectomy is expected to be the most effective in advanced disease therapy, with the benefit of avoiding thoracotomy. Hence, Aquino introduced the esophageal muscle tunic preservation technique in 1996 with the preservation of the stomach's skin tunic at the level of mediastinum, as well as the transposition of the stomach to the cervical region within this tunic for the reconstruction of digestion.

Source link: https://doi.org/10.5772/intechopen.99944


Audit of Surgical and Pneumatic/Hydrostatic Treatment of Achalasia in a Defined Population

All patients in the Nottingham area who suffered with achalasia between 1959 and 1983 were identified with achalasia. A retrospective investigation was carried out of all the patients who suffered with achalasia between 1959 and 1983. Early cardiomyoty was associated with a reduced recurrence rate than bag dilatation surgery, but it was followed by a longer stay in hospital and a higher risk of complications such as empyema, chest infections, and oesophageal tighture.

Source link: https://doi.org/10.1177/014107688607901206


A Comparison of Achalasia Quality of Life Index and Eckardt Scores in Assessing Severity of Achalasia Cardia and Prognosis at 3 Months - A Single-Center Prospective Observational Study

Background: Both scoring methods used in achalasia, Eckardt's score and Achalasia's quality of life score, are used in achalasia. Methods: In this review, 40 patients with achalasia cardia were included. After 3 months of baseline data in both the LHM and the ASQ groups, but not in the ISDN group, there was a significant decrease in both Eckardt score and ASQ scores. All of the patients who were classified as treatment success by the Eckardt score were also classified as such by the ASQ score. The percentage decline in Eckardt's score was found to be more prominent in the LHM and the PD groups than in the ISDN group. Conclusion: Both the Eckardt score and Achalasia quality of life questionnaire are equally effective at determining treatment response in achalasia cardia.

Source link: https://doi.org/10.23958/ijirms/vol07-i07/1437


Long-Term Outcomes of Per-Oral Endoscopic Myotomy (POEM) for Achalasia: a Systematic Review and Meta-analysis.

Background: The long-term effects of esophageal peroral endoscopic myotomy are still uncertain. Methods: We searched electronic databases for research assessing outcomes after POEM for esophageal achalasia, with a minimum median follow-up duration of 36 months. The rates of clinical success and post-operative reflux were estimated and compared to the same values at 12/24/36 months when available. Three cases of peptic strictures and one Barrett's esophagus were reported. Conclusions: In almost 80% of patients with achalasia, long-term clinical value of POEM persists. Chronic reflux, symptoms of Post-POEM reflux, seems to have remained stable over time. Barrett's esophagus and peptic strictures seem minimal.

Source link: https://doi.org/10.1055/a-1894-0147


Heller Myotomy versus Heller Myotomy with Dor Fundoplication for Achalasia

Can the addition of a Dor fundoplication to a Heller myotomy minimize the incidence of pathologic gastroesophageal reflux, according to the main issue. The chapter briefly reviews other relevant studies and results, discusses the implications, and concludes with a concrete case involving the treatment of a patient with either Heller myotomy or Heller myotomy plus partial fundoplication.

Source link: https://doi.org/10.1093/med/9780199384075.003.0040


Short-term and long-term results of pneumatic dilation in the treatment of patients with esophageal achalasia: 16 years of experience

This retrospective review details about 16 years of experience with pneumatic dilation in the treatment of patients with achalasia. Patients and methods: Patients with acute achalasia treated with endoscopic balloon dilation therapy were retrospectively reviewed by retrospectively. The achievement of endoscopic pneumatic dilation was described as no other than pneumatic dilation, according to the individual's health, and overall clinical Eckardt average score u2264 3. Two patients had periprocedural oesophageal perfusion, and in eight patients, the treatment effect was ineffective. In 8/140 and four PDs in 3/140, out of all patients, 107/140 had just one PD, 22/140 had two PDs, three PDs, and three PDs were administered in 22/140. Endoscopic balloon dilation, beginning with a 35 mm balloon, is an effective treatment for achalasia in the short and long term with minimal morbidity. The potential incomplete effect of dilation therapy is more apparent in a younger period than the initial dilation therapy.

Source link: https://doi.org/10.48095/ccgh2022236


Esophagus-Related Symptoms in First-Degree Relatives of Patients with Achalasia: Is Screening Necessary?

Methods: In this research, we investigated the frequency with which symptoms connected with esophageal function in first-degree relatives of patients with achalasia to see if screening is helpful and justified against the backdrop of early diagnosis in a genetically predisposed population. The frequency of swallowing difficulties in our population of relatives doesn't appear to have increased in comparison to the prevalence of dysphagia in the general population of 7-10% up to 22 percent, as documented in the literature.

Source link: https://doi.org/10.1159/000445790


Evaluating the Non-conventional Achalasia Treatment Modalities

Achalasia is the most common esophageal dysmotility disorder. Conclusions Non-conventional pharmaceutical approaches for treating achalasia include medical, endoscopic, and surgical procedures. Clinicians and patients alike need to know all of the techniques for the treatment of achalasia.

Source link: https://doi.org/10.3389/fmed.2022.941464

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions