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Acetyl cysteine - Europe PMC

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Last Updated: 13 November 2022

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N-acetyl-l-cysteine and alpha lipoic acid are protective supplement on human sperm parameters in cryopreservation of asthenoteratozoospermia patients.

The aim of this research is to determine the beneficial effects of N-acetyl-cysteine, alpha lipoic acid, and a mixture of NAC + ALA supplement in freezing medium in asthenoteratozoospermia patients. Thirty's freshly ejaculated semen samples were cryopreserved with sperm freezing medium as a control group and three group that SFM supplemented with NAC, ALA, and their combination NAC+ ALA also greatly enhanced sperm motility, availability, and DNA fragmentation. In addition, NAC and ALA groups showed a significantly higher prevalence of the NRF2 gene in comparison to other groups.

Source link: https://europepmc.org/article/MED/36321244


Antibiofilm Combinatory Strategy: Moxifloxacin-Loaded Nanosystems and Encapsulated N -Acetyl-L-Cysteine.

Staphylococcus aureus bacterial biofilms, which are implanted on implants, have a major effect on the increasing number of antimicrobial resistance cases. Using the microtiter plate biofilm technique, the nanosystems alone showed a significant decrease in both S. aurus biofilm viability and biomass. Biofilm viability was determined by using a combination of MOX-loaded and NAC-loaded nanosystems. Biofilms grown inside polyurethane catheters were also used to investigate the effect of combining MOX-loaded and NAC-loaded nanosystems on biofilm viability. Nanosystems, as carriers of bactericidal and matrix-disruptive agents, are thus a promising combinatory tactic toward the elimination of S. aureus biofilms.

Source link: https://europepmc.org/article/MED/36365113

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions