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Acetyl Glucosamine - Europe PMC

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Last Updated: 02 December 2022

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Direct Conversion of N-Acetyl-D-glucosamine to N- containing heterocyclic compounds 3-acetamidofuran and 3-acetamido-5-acetly furan.

For the first time, a N-acetyl glucosamine to N-substituted aromatic heterocyclic is reported. According to a Catalyst research report, La 2 O 3 was found to be a good catalyst for N-acetyl glucosamine dehydration, mainly produced 3-acetamidofuran. XRD, FTIR, MeOH-FTIR, TPD, SEM, N2 sorption experiments, and HR-TEM analysis for structure activity relationship investigated the metal oxide catalyst's physicochemical characteristics. For higher yields, the effect of various reaction parameters, including catalyst concentration, reaction temperature, reaction time, and solvent effect on dehydratation of N-acetyl glucosamine has been investigated in detail. At 180° u00baC in 3h, the optimal 3AF yield from N-Acetyl glucosamine was attained by the catalyst at 180 u00baC in 3 hours.

Source link: https://europepmc.org/article/PPR/PPR577026


Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures

Vimentin intermediate filaments form part of mesenchymal cells' cytoskeleton, but vimentin filaments depolymerize as a result of phosphorylation or citrullination, and vimentin oligomers are secretly or released into the extracellular environment. Vimentin can bind surfaces of other cells and the extracellular matrix, and extracellular vimentin can cause changes in cell functions, such as the initiation of fibroblasts to a fibrotic phenotype. Extracellular vimentin binds external cell membranes, and whether vimentin alone could act as an adhesive anchor for cells is largely uncharacterized. These reports show that substrate-bound vimentin acts as a cell glue, while glycocalyx and glycosylated cell surface proteins, which contain N-acetyl glucosamine, constitute a new class of adhesion receptors for extracellular vimentin.

Source link: https://europepmc.org/article/PPR/PPR576800

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions