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goutta accaccys spectrum is a late-prescription cesarean hysterectomy to reduce maternal morbidity. This study seeks to investigate the effects of surgical planning during this gestational age on neonates as a vital part of the pregnancy dyad. Conclusions: The use of neuraxial anesthesia in cases of PAS is a modifiable step that may enhance neonatal outcomes from cesarean hysterectomy as gestational age is not changeable in PAS cases.
Source link: https://doi.org/10.1515/jpm-2022-0062
Placenta accacconta spectrum disorders are severe pregnancy problems that arise as extravillous trophoblast cells invade outside the uterine inner myometrium and are characterized by hypervascularity on prenatal ultrasound and extreme postpartum hemorrhage. We investigated the pathological landscape of invasive PAS placenta and deciphered an evolving differentiation pathway from progenitor cytotrophoblasts to EVTs via LAMB4+ and KRT6A + CTBs, with single-cell RNA-sequencing analysis on the representative invasive parts and the normal part obtained from the same PAS placenta.
Source link: https://doi.org/10.3389/fcell.2022.1044198
Goals: The Placenta Accta Spectrum significantly raises the degree of childbirth and frequently involves urologic organs. At a centralised, tertiary referral center, we wanted to analyze urologic treatments in patients with PAS. Methods An examination of a prospectively collected data set involving all women presenting with PAS at our organization between November 2013 and June 2019. On MRI, fifteen patients had suspicion of bladder disease. Two patients had ureteric catheters placed, 14 required bladder repair, and two others suffered from ureteric injuries. Conclusions: PAS often needs Urological intervention to prevent and treat injury to the urinary bladder and ureter.
Source link: https://doi.org/10.48083/olra4694
Placenta previa and recent cesarean section procedures are two key risk factors for PAS disorders. The aim of this investigation was to find candidate biomarkers that could be used in the diagnosis and follow-up of PAS with machine learning techniques. In this research, proteomic data obtained from 26 women with and without PAS was used to generate proteomic data. Machine learning models were created with 5-fold cross-validation after using the Lasso method as the variable selection method. When the performance measurements of the two models are compared, the best result is likely to the XGBoost machine learning model. In addition, it can be argued that KDR and AMH proteins are candidate biomarkers that can be used in the diagnosis and follow-up of PAS as a result of the model's significance.
Source link: https://doi.org/10.52876/jcs.1180200
Methods This retrospective cohort research, conducted in a tertiary teaching hospital, included all women who underwent conservative care for PAS between January 1990 and December 2000. Results The study included 134 women with PAS who were administered conservatively and 134 controls with normal deliveries matching parity and age. There were 345 pregnancies among 107 women who attempted reproduction after conservative medical care for PAS vs. 339 pregnancies in the control group, versus 339 pregnancies in the control group after the index introduction. In the control group, 94 percent of women who attempted pregnancy following conservative medical care for PAS 99 gave live newborns vs. 94. Conclusion Following conservative medical therapy for PAS, women in PAS require additional procedures due to persistent placenta and/or heavy vaginal bleeding. There were no signs of fertility impairment in women post-conservative therapy for PAS.
Source link: https://doi.org/10.3389/fmed.2022.992215
The results of prophylactic balloon occlusion of the internal iliac artery in PAS patients remain uncertain. The patients were divided into two groups by the clinical information of 104 patients with placenta previa who were delivered by caesarean section between January 2016 and January 2019, were divided into two groups. According to the bleeding status after surgery, the study group underwent internal iliac artery preset balloon occlusion before caesarean section and uterine artery embolization, although the control group did not perform internal iliac artery preset balloon occlusion before caesarean section. There were no significant differences between the patients with invasive placenta, blood loss, and caesarean hysterectomy rates among the patients. In the absence of invasive placenta, Balloon occlusion of the internal iliac artery is most effective for haemostasis previa. Heart disease and thrombus formation are two possible consequences of the prophylactic use of internal iliac artery balloon occlusion.
Source link: https://doi.org/10.1186/s12884-020-03041-4
A greater number of repeated cesarean sections result in a greater risk of placental growth into the scar tissue of the uterus. Two clinical reports report on placental transplantation by organ-preserving surgical treatment of placental ingrowth with preservation of reproductive function and establishment of a more realistic prognosis for future reproductive studies due to the lack of two scars on the uterus in two separate localizations. Following fetal extraction and the possibility of intraoperative complications such as bladder, ureteric, and intestinal injuries, early dissection of adhesions in order to gain access to the surgical site is critical and minimizes the blood loss. The stage of fundal cesarean tissue formation is removed from surgical strategies in organ-preserving placental ingrowth, and it requires the cesarean section at the border of the uterine-placental hernt and the body of the uterus, which needs subsequent metroplasty.
Source link: https://doi.org/10.24060/2076-3093-2022-12-3-230-236
A statistical analysis of serum chorionic gonadotropin associated with pregnancy of plasma protein A and alpha-fetoprotein, based on the findings of a nationwide screening program, found a significant rise in the results of all the studied pregnancy proteins in women with a scar on the uterus and placenta acctera, compared to the group of pregnant women without scarcity or no abnormalities of attachment of the placenta. PAPP-A - 2. 65 times The risk of placenta in women with a scar on the uterus in cases of exceeding the diagnostic threshold of AFP concentration increased 2. 5 times.
Source link: https://doi.org/10.18821/0869-2084-2020-65-6-353-357
In cases of placenta previa overlying a previous cesarean section scar, the risk of placenta spectrum disorders is the highest. Placenta accaccaccemia spectrum disorders in Portugal have been evaluated by a few studies. Result: Only cases with histopathological evidence of placenta areta were included during the study period, including a cesarean section scar were diagnosed.
Source link: https://doi.org/10.20344/amp.14001
Background: Placenta accaccacca spectrum disorder is a significant life-threatening disorder. Methods: This is a case-control study based on the results from a large tertiary referral university hospital in Ahvaz, southwest of Iran, in Ahvaz, southwest of Iran. 187 cases were diagnosed with placenta accacc, from 2015 to 2020, and 552 controls without PAS were included in the study. With a 95% confidence interval, a multivariable logistic regression model was used to find independent risk factors. Results: During the study period, there were 3. 7/1000 deliveries during the study period. Prior cesarean delivery, multiparity and multigravidity were discovered, as well as placenta previa, as the independent risk factors of PAS. Conclusion: The frequency of PAS is similar to that in other groups. The most significant problems, according to prior cesarean delivery, placenta previa, multigravidity, and multiparity, were independent risk factors, as well as perinatal hysterectomy and preterm birth.
Source link: https://doi.org/10.18502/jri.v23i4.10814
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