Advanced searches left 3/3

Acanthosis - Europe PMC

Summarized by Plex Scholar
Last Updated: 10 November 2022

* If you want to update the article please login/register

Acanthosis Nigricans: Pointer of Endocrine Entities.

Acanthosis nigricans has been identified as a result of insulin resistance in Acanthosis nigricans. Objective: We aim to examine AN from an endocrine and metabolic perspective focusing on IR in connection with metabolic disorders such as obesity, diabetes mellitus, and metabolic syndrome with or without polycystic ovary syndrome. PubMed recently updated English papers on PubMed, covering journals from the last five years. Despite increased prevalence of obesity and MS in younger populations, an alarming rise in cases of obesity and MS has been identified. For example, in cases involving sulcus cutis, hyperpigmented spots, crista cutis, and papillary studies, Dermoscopic examination is often needed. A skin biopsy may be needed, but it is not the rule. Both IR that clinically manifests obesity/MS correlates with AN; most studies are cross-sectional, with just a few longitudinal ones. AN was found with type2DM, as well as type 1DM. In 60-80% of cases, females with PCOS may already have metabolic disorders, with an that matches the relevant skin color. AN administration is dependent on underlying conditions, and specific dermatological therapy is not always recommended, unless the patient achieves metabolic control, has excessive skin lesions, or wants cosmetic enhancements. Lifestyle changes in IR cases, from weight control to bariatric surgery, can help. Metformin, a drug whose use is extended to PCOS and even to AN itself outside of the narrow panel of glucose anomalies, is a key player in oral medication against DM type 2, a drug whose effects are extended to PCOS and even to AN itself.

Source link: https://europepmc.org/article/MED/36292208

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions