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Abscess - ClinicalTrials.gov

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Last Updated: 11 January 2023

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The Effects of Dexamethasone on the Time to Pain Resolution in Dental Periapical Abscess

The severity of dental pain can have a major effect on an individual's quality of life. Many times seeking relief from their dental pain are directed to the emergency department, dental anesthesia injections, or oral pain medications. The aim of our study was to determine if oral steroids would influence the time until patient symptoms of improvement in their dental pain. Steroids are a commonly used anti-inflammatory drug in the Emergency Department for the purpose of pain relief from throat pain. As the periapical infection pain is predicted to be largely from the pressure, we suspect that steroids' anti-inflammatory properties may reduce the inflammation, thus the pressure, and may lead to a decrease in time until the patient's pain eases.

Source link: https://clinicaltrials.gov/ct2/show/NCT03005522


A Randomized Controlled Trial for Conservative Management of Cutaneous Abscess Using Topical Anesthetic in Children as Compared to Standard Management

Cutaneous absces are a common problem in the pediatric population, resulting in a significant number of emergency room and primary care visits each year. Historically, medicine was based on antibiotics and surgical drainage, but as our knowledge of these disease processes has expanded, we have moved away from surgical drain surgery only when absolutely necessary. The application of topical anesthetic cream to a cutaneous absces beneath a non-permeable dressing has been shown to increased rates of spontaneous drainage. This is a single center non-blinded placebo controlled trial of topical anesthetic cream to standard care for superficial, non-perianal absces in children under the age of 18 years. The secondary outcomes are a return to the emergency room/hospital/care provider and the need for incision and drainage. Information on patient outcomes using standardized patient reported outcome measures for health-related quality of life will also be collected.

Source link: https://clinicaltrials.gov/ct2/show/NCT05461053

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions