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Abortion - PubAg

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Last Updated: 15 October 2021

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Spontaneous Abortion and Chikungunya Infection: Pathological Findings

Intrauterine transmission of the Chikungunya virus throughout early pregnancy has rarely been reported, although vertical transmission has been observed in infants. Below, we report 4 instances of spontaneous abortion in ladies that became infected with CHIKV between the 11th and 17th weeks of maternity. Furthermore, by immunohistochemistry, we discovered a positivity for the anti-CHIKV antibody in cells of the endometrial glands, decidual cells, syncytiotrophoblasts, cytotrophoblasts, Hofbauer cells and decidual macrophages. Electron microscopy also helped in recognizing virus-like fragments in the aborted material with a diameter of 40-- 50 nm, which followed the size of CHIKV fragments in the literature. Our searchings for in this research suggest early maternal fetal transmission, including more evidence on the duty of CHIKV in fetal fatality.

Source link: https://pubag.nal.usda.gov/catalog/7353031


Ovine abortion and stillbirth investigations in Australia

Fetal loss and lamb mortality between mid‐pregnancy and discouraging are essential financial and welfare problems for the Australian sheep sector. Information for 529 examinations on abortion or stillbirth between 2000 and 2018 were recovered from four state vet labs in Western Australia, South Australia, Victoria and Tasmania. Investigations that included placental cells samples were even more than two times as most likely to have an aetiological medical diagnosis compared to examinations without placenta. Of the examinations where an aetiological diagnosis was made, 81% involved infectious abortion, with Campylobacter spp. Some conditions that cause abortion in Australian lamb have zoonotic potential, and vet professionals play a vital function in enlightening clients about ideal health when handling lambing and expecting ewes or any aborted material.

Source link: https://pubag.nal.usda.gov/catalog/7297400


Chlamydia pecorum–Associated Sporadic Ovine Abortion

Despite previous discovery of Chlamydia pecorum in occasional ovine abortions, released descriptions of naturally taking place infections with fetoplacental lesions are lacking. C. pecorum was recognized utilizing a targeted qPCR assay, which also determined infectious load within fetal cells. The existence of feasible C. pecorum in fetal examples was verified by cell culture. Multilocus series typing data suggested that the C. pecorum stress from each unborn child were the same and of series type 23. This report confirms C. pecorum as a most likely root cause of ovine abortion and gives the first descriptions of linked fetoplacental sores in normally infected sheep.

Source link: https://pubag.nal.usda.gov/catalog/7243294


Adoptive cell therapy with induced regulatory T cells normalises the abortion rate in abortion-prone mice

Ovarian hormones drive invivo generation of regulatory T cells throughout maternity. CD4+CD25- T cells were separated from the spleens of CBA/J mice and promoted with either 17β-oestradiol, progesterone or changing growth factor-β1 plus retinoic acid for 4 days to generate caused Tregs. On Days 1-- 4 of gestation, DBA/2-mated pregnant CBA/J women mice were infused intravenously with iTregs or Tregs separated from normal BALB/c-mated pregnant CBA/J mice. Product interferon -γ and uterine forkhead box p3 expression was evaluated by ELISA and immunohistochemistry respectively. Using a 3H-thymidine consolidation assay, isolated CD4+CD25+ Tregs generated by the various treatments reduced the spreading of CD4+CD25- T cells. Immunohistochemistry revealed significantly greater Foxp3 expression in gravid wombs from mice injected with np-Tregs and P4-induced iTregs than in the phosphate-buffered saline-treated team. The findings of this study suggest a prospective therapeutic advantage of invitro-induced Tregs in patients with reoccurring abortion.

Source link: https://pubag.nal.usda.gov/catalog/7264114


Observation of Embryo Abortion Characteristics of Ziziphus jujuba Mill. ‘Zhongqiusucui’

To determine the embryo abortion pattern and create a structure for further research study, the embryo abortion qualities of Z. jujuba Mill. Large jujube fruits had a relatively low embryo abortion rate. Tiny jujube fruits had a reasonably reduced kernel content rate and high embryo abortion rate. The third set of jujube fruits differed considerably from the first and 2nd sets. The embryo abortion level of jujube fruits on the lignified bearing shoot was more than that on the nonlignified bearing shoot, and the chance of jujube fruit with double kernels on the nonlignified bearing shoot was greater than that of the fruit on the lignified bearing shoot. The embryo abortion rates of jujube fruits with a smaller sized fruit form index and bigger fruit form index were reduced, and that of the medium was greater. Fractured jujube fruits did not contain normal seed kernels and their embryo abortion rate was 100%.

Source link: https://pubag.nal.usda.gov/catalog/7409015


Genome-wide transcriptome analysis of microspore abortion initiation in radish (Raphanus sativus L.)

The usage of male sterilized lines is among the ideal methods in hybrid seed manufacturing. In this study, histological evaluations of flower buds from a CMS line 40MA and its corresponding maintainer line 40MB were performed, which show that microspore abortion was started shortly after the tetrad stage. RNA sequencing was done to analyze the transcriptomes of floral buds from the early microspore and the tetrad stage phases of these 2 lines. According to the irregular look of the tapetum cells in 40MA, a series of tapetum growth relevant genetics were screened and assessed. Furthermore, an overall of 623 genetics with differential expressions in the tetrad phase, yet not in the very early microspore phase in between both lines were filteringed system as the microspore abortion initiation associated prospects.

Source link: https://pubag.nal.usda.gov/catalog/7411341


Infectious Abortions in Small Ruminants: Challenges for Diagnosis and Public Health

In early 2017, abortions happened in ∼ 70% of goats and 66% tested positive for Coxiella burnetii and 40% of goats were favorable for Chlamydophila abortus. In February 2018, the exact same herd reported an abortion rate of 75%, with 55% positive for C. burnetii, 36% for C. abortus, and 22% for Toxoplasma gondii. 6 goat milk samples were positive for C. burnetii by molecular evaluation. C. burnetii could be taken into consideration as the primary reason for abortions in the first and 2nd year.

Source link: https://pubag.nal.usda.gov/catalog/7347545


Prevalence of Coxiella burnetii Antibodies in Dairy Cattle Associated with Abortions and Reproductive Disorders

In this research, the investigation on the prevalence of Coxiella burnetii antibodies in cattle dairy products farms associated with a history of abortions/ and reproductive problems located in different geographical areas in various states of India was accomplished. Further, the seropositivity of the milk farms [84. 1%] suggests at the very least 1 or 2 animals in each ranch was located to be positive for C. burnetii antibodies. This study revealed that C. burnetii infection prevailed in dairy livestock connected with abortions, infertility, and other reproductive problems and it indicates the livestock have a duty as a tank and may function as a prospective zoonotic resource to ranch linked risk-groups employees namely farmers, pet handlers, veterinarians, and so on, that necessitates the adoption of appropriate mitigating techniques to minimize the occurrence of Q fever in livestock dairy ranches.

Source link: https://pubag.nal.usda.gov/catalog/7414720


Retrospective study of factors associated with bovine infectious abortion and perinatal mortality

Nevertheless, the relative contribution of virus to bovine abortion and perinatal mortality is inadequately recorded, since available studies entailed just a limited number of virus. The purposes of the existing surveillance study were to identify the frequency of transmittable agents associated with bovine abortion and perinatal mortality, and to recognize differences in manufacturing type, gestation size, parity and seasonality by using combined effect models. At least one potential causal agent of the abortion or perinatal mortality was spotted in 39 % of situations. Neospora caninum [odds ratio: 0. 4; 95 % self-confidence period: 0. 3-- 0. 7] and Aspergillus fumigatus were found much less in early versus late pregnancy. Aspergillus fumigatus was less common in dairy in comparison to beef abortion cases. Winter months was connected with a reduced positivity for Neospora caninum and BVDv in comparison to warmer periods.

Source link: https://pubag.nal.usda.gov/catalog/7355225


Meningoencephalitis, Vasculitis, and Abortions Caused by Chlamydia pecorum in a Herd of Cattle

A cow milk close to a sheep group had third-trimester abortions and fatalities in cows and calves over a 14-month period. Seventeen of these affected fetuses had intracytoplasmic bacteria in endothelial cells, and 1 unborn child with pericarditis had similar microorganisms within mesothelial cells or macrophages. Immunohistochemistry for Chlamydia spp. In 1 calf and 11/11 unborn children, C. pecorum PCR amplicon series were 100% homologous to published C. pecorum sequences. Enzootic chlamydiosis as a result of C. pecorum was the determined root cause of the late term abortions and the vasculitis and meningoencephalitis in cows, unborn children, and calves.

Source link: https://pubag.nal.usda.gov/catalog/7353249

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions