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Abdominal Hysterectomy - Springer Nature

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Last Updated: 10 December 2022

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Preoperative Misoprostol to Reduce Blood Loss and Related Morbidities During Abdominal Hysterectomy: a Systematic Review and Meta-analysis of 10 Randomized Placebo-Controlled Trials

During abdominal hysterectomy, the aim of this research is to conduct a meta-analysis of all randomized controlled trials that investigated the effectiveness and safety of preoperative misoprostol versus placebo. In a random-effects model, the findings were summarized as mean difference and risk ratio with 95% confidence intervals. Compared to the placebo group, the mean intraoperative blood loss, mean difference in hemoglobin drop, and the mean length of hospital stay were both drastically reduced in favor of the misoprostol group. Preoperative administration of misoprostol was generally safe and linked to a substantial decrease in blood loss-related morbidities among patients undergoing abdominal hysterectomy.

Source link: https://doi.org/10.1007/s43032-022-01121-8

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions