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Compared to open surgical surgery, endovascular therapies for aneurysms of the abdominal aorta are getting more popular. Endovascular therapy is less invasive, and the mortality rate is much lower in comparison to open surgical treatment. The occurrence of permeability or endoleak is one of the challenges of endovascular treatment of abdominal aortic aneurysm. We investigated the prevalence and characteristics of endoleaks in patients treated endovascularly for abdominal aortic aneurysm in this book. The Clinical Department for diagnostic and interventional radiology, University Hospital Split, was based on statistical analysis of 60 patients who were treated at the Clinical Department for diagnostic and interventional radiology. Endoleak type II, the most common type of endoleak that occurred was endoleak type II. Endoleak type II patients in the majority of patients, eventually recovered and did not require re-intervention. The patients included in this research's average follow-up time was 26 months.
Source link: https://doi.org/10.55378/rv.46.2.1
We want to objectively compare the safety and effectiveness of CL and standard limb therapy in patients receiving EVAR as a result of a recent cohort study conducted in our center. Based on the findings of our previous research, a total of 275 patients who meet the inclusion criteria will be enrolled and ranked with a 4:11 ratio of CL to SL. Both patients and surgical medications will be administered by the same perioperative and postoperative drugs. All EVAR procedures will be carried out under strict protocols, using Endurant II or IIs Stent Grafts. Surgeons and physicians will determine the graft stent's configuration by final angiography. Introduction to this Endovascular Repair trial This crosseD vs. stANdard Configuration in Endovascular Repair is the first non-randomized controlled trial to compare these two graft configurations in EVAR, to our best knowledge. The main aim is to compare the MALEs between two groups at three years postoperatively.
Source link: https://doi.org/10.3389/fcvm.2022.1046200
Acute kidney injury as a result of open and endovascular repair of thoracoabdominal aneurysm is a leading predictor of mortality and postoperative complications. We tested tissue inhibitor of metalloproteinase 2 and insulin-like growth factor-binding protein 7 as a single early biomarker for AKI detection and prediction of patient outcomes in U19. Mean patient age was 64. 5 years old, and endovascular treated patients were older. Patients undergoing open or endovascular surgery were found to have a significant difference in TIMP2 u00d7 IGFB7 levels at no time. With AKI requiring temporary renal replacement therapy, the predictive quality of the TIMP2 u00d7 IGFBP7 estimate on ICU admission was positive. TIMP2 u00d7 IGFBP7 level measured 6u201312 hrs postoperatively and may be a useful early detectable biomarker for AKI requiring temporary renal replacement therapy.
Source link: https://doi.org/10.1024/0301-1526/a000902
Evidence reveals that infrarenal aortic aneurisms and aortoiliac occlusive disease in women are different than in men in terms of anatomical structure and more intensive clinical course. In patients with abdominal aorta and aortoiliac occlusive disease, the aim was to investigate gender-based differences in histopathology of abdominal aorta. The adventitia in the aneurysmal neck is greater in women than in men, according to MMP-9. The MMP-9 expression in the media and adventitia is higher among men with aneurysm than in others with occlusive or stenotic lesion. In comparison to women, nearly all indices of the aortic wall reconstruction and MMP-9 expression match with each other in men with the aneurysm. Women and men can be evaluated by a variety of aortic aneurysm and aortoiliac occlusive disease.
Source link: https://doi.org/10.24884/1607-4181-2022-29-3-106-117
For the first time in this review, after abdominal EVAR, the CE-CTA and non-CE QISS-MRA were compared. After EVAR at their first follow-up examination, our research included 20 patients who underwent radical QISS-MRA and CE-CTA. Aneurysm sac diameter measurements can be inaccurate by up to 1 cm in CE-CTA due to hyperdense artifacts in CE-CTA causing hyperdense artifacts causing hyperdense artifacts, causing hyperdense artifacts in CE-CTA. When compared to radial QISS-MRA, Type 2 endoleaks with low-flow characteristics in CE-CTA were ignored. Except for type 2 endoleaks, where cooperation was strong, the interobserver agreement between CE-CTA and QISS-MRA was nearly flawless, except for type 2 endoleaks, where agreement was robust. Following abdominal EVAR, Radial QISS-MRA is a contrast agent-free method for diagnosing and monitoring all forms of endoleaks and aneurysms in patients. It provides information about specific clinical issues concerning aneurysm size, the presence and types of endoleaks without radiation exposure, as well as the side effects of iodine-based contrast agents.
Source link: https://doi.org/10.3390/jcm11216551
In this report, we wanted to find differences in the aneurysm sac pressure between patients undergoing BEVAR and MFM implantation. SPI and PPI were lower in the BEVAR group after the procedure than in the MFM group. During a surgical procedure, a decrease in SPI and PPI was identified in patients undergoing BEVAR, however no changes were made in the MFM group. BEVAR, not MFM, is correlated with a decrease in systolic and pulse pressure in the aneurysm sac in patients with TAAA, but not MFM.
Source link: https://doi.org/10.3390/ijerph192114563
Warfarin use in patients with ruptured AAA can make surgical intervention more difficult and impact prognosis. This case highlighted coagulopathy in AAA, anticoagulation reversal agents used, and stressed the importance of rigorous coagulation profil monitoring in managing AAA.
Source link: https://doi.org/10.31674/mjmr.2022.v06i04.007
This research looked at the long-term effects of patients treated with open surgical repair for acute abdominal aortic aneurysms. In fifty patients, long-term chronic renal decline was evident, largely in conjunction with post-operative acute kidney injury. With stable results, the present study indicates that open c-AAAAA repair can be carried out with acceptable operative risk and durable results. To ensure the best long-term outcome, complex AAA open surgery repair should be carried out in high-volume aortic centers and tailored to the patient.
Source link: https://doi.org/10.3390/jpm12101630
Abstract Background Abdominal aneurysm is a common life-threatening cardiovascular disease that affects middle-aged and elderly people. Autophagy may play a role in AAA's pathological process, according to previous experimental findings, but the pathogenesis of autophagy in AAA remains uncertain. Through bioinformatics analysis, we hope to identify and validate key autophagy-related genes involved in AAA in order to better understand the mechanisms of autophagy dysregulation in AAA. Methods The GSE57691 microarray database was downloaded from the Gene Expression Omnibus database, containing 49 AAA samples and ten common aortic samples. From the Human Autophagy Database, 232 autophagy-related genes were found. The GSE57691 dataset was tested for differentially expressed autophagy-related genes involved in AAA. Using the STRING database, key gene cluster modules were identified using the MCODE Cytoscape plugin, and hub genes in AAA related DE-ARGs were tested using the Cytospace plugin. The final key genes were identified by comparing the LASSO calculation results and hub genes, and their expression levels were further verified in AAA aortic samples by qRT-PCR. Eventually, the transcription factor regulatory networks and target drugs of these key genes' key genes were predicted by the JASPAR database and DSigDB database, respectively. These results add to the diagnosis and prognosis of AAA autophagy dysfunction, and they may contribute to AAA's diagnosis and prognosis.
Source link: https://doi.org/10.21203/rs.3.rs-2184838/v1
Endovascular aneurysm repair has become the most common treatment technique for ruptured infrarenal abdominal aneurysm. This paper investigates the effect of endograft type on perioperative outcomes for ruptured infrarenal abdominal aortic aneurysm in this region. Only patients treated for ruptured infrarenal abdominal aneurysm were included. The patients treated with Zenith had significantly lower body mass index and were less likely to be white compared to patients treated with Excluder or Endurant. On the other hand, patients treated with Endurant were less likely to be smokers. Patients treated with Zenith had a dramatic ruptured infrarenal abdominal aneurysm diameter. Patients with ruptured infrarenal abdominal aneurysm without hypotension were not affected by hypotension, but not significantly so. Conclusions This report presents the most recent findings of endovascular aneurysm repair for ruptured infrarenal abdominal aneurysm with relatively low mortality.
Source link: https://doi.org/10.1177/1708538120947859
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