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Abdominal - ClinicalTrials.gov

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Last Updated: 10 September 2022

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Brain and Abdominal Aneurysm Study (BAAS)

Aortic Aneurysm is also a significant public health issue, due to a high lethality. Screening has effectively reduced mortality from an aortic aneurysm rupture, but a substantial number of people who die did not have a diagnosis of aortic aneurysm prior to rupture. The reason for this program is that opportunistic testing for abdominal aortic aneurysms may be beneficial in patients with aneurysmal subarachnoid hemorrhage. In all cases of a SAH that has been submitted to MCH for care, the investigators intend to screen for AAA. If no one out of 81 consecutively screened patients of aSAH has evidence of AAA, the investigators can have a high likelihood of finding an AAA in the patient population.

Source link: https://clinicaltrials.gov/ct2/show/NCT01420991


Contrast Enhanced Ultrasonography for Blunt Abdominal Trauma Imaging in Children

Hypothesis and Aims Hypothesis: Hypothesis and Aims: Hypothesis: Contrast enhanced ultrasound has good sensitivity and specificity when compared to a gold standard CT scan for the detection of intra-abdominal solid organ injury in hemodynamically healthy children with blunt abdominal trauma. In hemodynamically healthy children with blunt abdominal trauma, this will be a prospective cohort study to determine the test characteristics of contrast enhanced ultrasound for the detection of intra-abdominal solid organ injury in children with blunt abdominal pain as compared to a gold standard CT scan. The study subjects will be aged 0-18 years, with hemodynamically healthy blunt abdominal pain, and for those who require an abdominal CT scan is required.

Source link: https://clinicaltrials.gov/ct2/show/NCT03490929


Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

Patients with autonomic dysfunction are characterized by disabling orthostatic hypotension as a result of severe autonomic nervous dysfunction. The purpose of this research was to determine the hemodynamic pathways by which abdominal compression raises the standing blood pressure and orthostatic tolerance in these patients' standing blood pressure and orthostatic tolerance, as well as those of the highest care midodrine. During head up tilt, the investigators will investigate the likelihood that abdominal compression will reduce stroke volume and the rise in abdominal vascular mass.

Source link: https://clinicaltrials.gov/ct2/show/NCT02429557


Survey Of Mobilisation and Breathing Exercises After Thoracic and Abdominal Surgery

Patients may also receive breathing assistance in connection with the surgery. There are similarities and differences in international practice regarding postoperative breathing training. There are studies that have mapped practice after mainly thoracic surgery but also abdominal surgery. However, there are no studies that have predicted when the recommended breathing exercises would begin after various types of operations. The aim of the research is to determine when mobilization and breathing training begins following abdominal and thoracic surgery, and what is then done. The study will be published as a quality follow-up to mapping of practice. Clinical benefit The article will show that clinical research will be published when this takes place and what is done, as well as the first one that shows when this training is started, and it will be the first analysis that shows when this training is started and how much money is spent. The first report on mobilisation will show that clinical research is the first one that shows when this training is ever administered.

Source link: https://clinicaltrials.gov/ct2/show/NCT04729634


Effects of Home-based TEA for Abdominal Pain in Patients With Irritable Bowel Syndrome (IBS)

The aim of this research is to investigate the possibility of TEA to treat abdominal pain in people with IBS with constipation. Participants with IBS-C also want to compare electrical neuromodulation therapy with medical neuromodulation therapy in their ability to treat abdominal pain and improve autonomic dysfunction. In participants with IBS-C, this research will explore the effect of three active treatment trials vs. a sham control intervention on abdominal pain and other IBS symptoms.

Source link: https://clinicaltrials.gov/ct2/show/NCT05519683


AI Assisted Doctors to Improve the Accuracy of Abdominal Pain Diagnosis: a Single Center Study

However, the corresponding diseases in the real clinical setting are numerous; in the face of challenging and heavy clinical research, the key problem to be addressed at present is how to extract the key characteristics of patients' diseases in order to achieve high-quality and accurate diagnosis and treatment. For example, abdominal pain is one of the most common medical signs of patients seeking medical care, and some acute abdominal pains, such as gastrocy, strangulated intestinal blockage, acute obstructive cholangitis, and other unusual medical signs include short treatment time window, and high mortality. Clinicians must make a quick diagnosis and distinguish between those that necessitate emergency intervention and those that do not in order to treat patients in a timely manner and avoid catastrophic events. However, abdominal pain's causes are numerous, and the mechanisms are complicated. In addition, because pain is a subjective sensation and is largely influenced by subjective circumstances, there are no objective measures to determine whether or not and the degree of pain, and it is extremely difficult to accurately diagnose and measure abdominal pain. To this end, the clinician must conduct a thorough history and conduct a thorough physical examination when assessing a patient's abdominal pain when assessing a patient's abdominal pain. The majority of these studies are focused on pattern recognition based on images, and the logical judgment based on natural language using medical records data is still in the preliminary development stage.

Source link: https://clinicaltrials.gov/ct2/show/NCT05497258


A Prospective Case Series Evaluating Surgimend Mp® In Patients Undergoing Complex Abdominal Hernia Repair

Large abdominal wall hernias are surgically difficult to repair and are often associated with significant postoperative complications. The placement of synthetic mesh in these high-risk patients raises the risk of mesh infection, enterocutaneous fistula formation, and mesh explantation. One of the larger studies of risk factors related to mesh explantation found that concomitant intra-abdominal procedures resulted in a greater risk of subsequent mesh explantation. As an alternative to synthetic meshes, bioprosthetic meshes derived from decellularization and processing of allogeneic or xenogeneic tissue sources have been introduced, and surgeons can often be able to address surgical site occurrences and repair the repair without the need for mesh explantation. The Ventral Hernia Working Group has reported low incidences of mesh infection and explantation among bioprosthetic meshes and explantation in these troubled patients and is recommending in those difficult patients based on the best available scientific evidence. To our knowledge, there are no prospective studies investigating the long-term clinical results for abdominal wall reconstruction procedures involving fenestrated macropourous biologic matrices, which may have led to tissue revascularization and integration of the biologic graft, as well as an expected improvement in overall results. SurgiMend MPu00ae's efficacy and results in the course of challenging ventral hernia repairs are the subject of this research, which is a prospective, case series study. This case series involves a biologically modified hernia mesh with no FDA approval for hernia repair. Subjects will be on a baseline visit where they will obtain a physical examination, complete quality of life questionnaires, and a pain scale.

Source link: https://clinicaltrials.gov/ct2/show/NCT03450473


Modified Purandare's Cervicopexy Versus Abdominal Sacral Hysteropexy as Conservative Surgeries for Genital Prolapse: A Randomized Control Trial

Pelvic organ prolapse, or the herniation of the pelvic organs to or above the vain walls, is a common disorder. Many women with prolapse have symptoms that influence daily activities, sexual stability, and exercise. POP can have a negative influence on body appearance and sexuality. Nulliparous prolapse is estimated to account for 1. 5% to 2% of all cases of genital prolapse. The number of young women who have had one or two children has increased to 58% to 58%. As this type of prolapse occurs at a young age, the surgical approach should not only reduce the prolapse but also maintain the reproductive function. Women of all ages are affected by Pelvic organ prolapse. POP surgical corrections can often reflect the nature and anatomical site of the dysfunctional support, but the surgeon must determine whether to perform this surgery vaginally or through the abdomen as an open or laparoscopic procedure. By criss crossing using No. 66, the uterine isthmus is fixed by a 25-30 cm long strip of polypropylene mesh to the rectus muscle is the center of the modified purandare's cervicopexy. Abdominal sacral hysterectomy remains a viable alternative for women undergoing pelvic reconstructive surgery who wish to preserve their uterus while still suffering from similar patterns of overall improvement and symptoms improvement. Avoiding hysterectomy reduces the likelihood of mesh erosion, but it does raise the possibility of subsequent recurrent prolapse, particularly in the anterior compartment.

Source link: https://clinicaltrials.gov/ct2/show/NCT04852991


Ultrasound Guided Quadratus Lumborum Block Versus Caudal Block for Pain Relief in Children Undergoing Lower Abdominal Surgeries

Regional anesthesia and analgesia techniques are often used during pediatric surgical surgery to aid pain relief, reduce parenteral opioid use, and improve post-operative pain management and patient satisfaction. The QL block is currently used as one of the perioperative pain management techniques for all ages of abdominal surgery. The local anesthetics can travel between the quadratus lumborum muscle and the medial layer of the thoracolumbar fascia, which is close to the thoracic paravertebral space. Many benefits can be obtained by using ultrasound guidance for peripheral nerve blocks. With a face mask containing sevoflurane 8% to 50% oxygen in air, and then an intravenous cannula will be introduced. If FLACC scale > 4. 10, patients in all study groups in PACU will be given as rescue analgesia for patients. Parents will be told of the pain assessment, and if patients had pain at home, parents would be urged to give oral paramol 30 mg/kg. Statistical Analysis Before the study, the sample size was estimated using the G* Power software version 3. 1. 7 analysis package. Using the statistical software for social science version 16, collected data will be computerized and analyzed. Mann Whitney U test to compare scores between two groups will be used to compare quantitative continuous variables between two groups to compare scores between two groups' quantitative variables, student trest for comparing quantitative continuous variables between two groups will be used for qualitative comparisons among two groups.

Source link: https://clinicaltrials.gov/ct2/show/NCT03646630

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions