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Carbon tetrachloride is just one of the hepatotoxic compounds that can trigger hepatic fibrosis. The aim of this research study was to know the impact of fermented soybean to IL-6 expression and ALT-AST level in rats that induced by CCl4. The outcome revealed that dose of 800 mg/kg BW was a reliable dose which has the greatest portion reduction both of hepatic IL-6 expression and ALT-AST level 81,16% and 46,45% respectively. The verdict was the fermented of soybean able to reduce the hepatic IL-6 expression and ALTAST level in caused CCl4 rats.
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