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API - Europe PMC

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Last Updated: 10 June 2022

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Untargeted metabolomics study and identification of potential biomarkers in the six sections of the genus Stachys L. (Lamiaceae) using HPLC-MQ-API-MS/MS.

"Introduction" is the product of the author's description "Introduction" The genus Stachys L. , which is related to the family Lamiaceae, is one of the oldest genera with outstanding medicinal properties. A large variety of secondary metabolites are present in plants of this genus. Stachys species' incomplete investigation of chemical profiles, we conducted untargeted metabolomics analysis and found potential biomarkers in six sections of Stachys of chemotaxonomic importance. Dried leaves of 17 taxa were used for analysis of all the constituents using HPLC-MQ-API-MS. In non-flavonoid chemicals, a total of six coumarins and six phenolic acids were present at high levels. According to a report, the taxonomic complexities of some Stachys species in sections Fragilicaulis, Aucheriana, and Setifolia had been properly addressed. "An HPLC-MS/MS-based metabolomics approach combined with multivariate statistical techniques was used to identify key indicators, analyze metabolic variability, and predict the pharmaceutical characteristics of Stachys species. ".

Source link: https://europepmc.org/article/MED/35670362


API-based evidence acquisition in the cloud - a survey

"Cloud services and cloud storage solutions are two specific challenges in digital forensic investigations. " Basic methods for extracting data from the cloud are explored and compared, using the example of 30 cloud storage services since accessing these data is extremely difficult. We introduce the concept of an API-based evidence acquisition for cloud services that use the service's officially approved API. In the survey context, we'll show how this strategy stacks up to the most popular cloud drive services. CLOUDxTRACT, a proof-of-concept acquisition platform that can gather evidence from a few cloud service providers, is the first glimpse of a proof-of-concept acquisition framework.

Source link: https://europepmc.org/article/PPR/PPR499876


API solubility in semi-crystalline polymer: Kinetic and thermodynamic phase behavior of PVA-based solid dispersions.

"The manufacture of a morphous solid dispersions trays as a promising remedy for many active pharmaceutical ingredients' poor bioavailability. " This paper was designed to investigate and compare polyvinyl alcohol-based solid dispersions made by hot-melt extrusion with their specific API-PVA temperature composition chart. In addition, the impact of API glass-forming capability on the LTPS was investigated through the selection of two APIs with contrasting GFA. In comparison, NAP reacted to a great degree in each analogous sample with an amorphous NAP content of 22. 5-23. 5 wt. "While the drafted T-C phase diagrams were still in accord with their respective LTPS research, they did not account for water uptake as well as potential HME-induced variations on the extrude glass-transition temperature. ".

Source link: https://europepmc.org/article/MED/35623485


Malware detection framework based on graph variational autoencoder extracted embeddings from API-call graphs.

"Malware abuses the confidentiality and integrity of the data that can cause material and moral harm to companies and individuals. " To minimize the size of graph node features extracted from Android apk files, this research developed a malware detection system based on API call graphs and used Graph Variation Autoencoder. To evaluate the GVAE-reduced's functionality, efficacy of the GVAE-reduced services, recursive feature elimination, and Fisher score were applied to select information feature sets with the same dimensions as GVAE-reduced embeddings. "Compared to only GVAE-reduced embeddings, the last carried out experiment that combined RFE selection's strengths and GVAE enhanced the results.

Source link: https://europepmc.org/article/MED/35634097


API-polymer interactions in Sepineo P600 based topical gel formulation- impact on rheology.

"Principation of API was evaluated after incorporation of API, with Acrylamide/Sodium Acryloyldimethyl taurate copolymer as a gelling agent. " Both gel and emulgels, such as viscosity, elastic moduli, and yield stress, were significantly affected by the pH of the topical formulations and API concentration, according to the study results, showing that the rheological characteristics of both gel and emulgel, as well as yield stress, were greatly affected by the pH of the topical formulations and API concentration. Interactions between API and polymer chains via electrostatic attraction may be a major factor in altering the rheology, which may have a major effect on the internal phase's physical stability against phase separation of the internal phase in emulsion gel samples. Sepineo P600 gel and emulsion gel are particularly suitable for use in semisolid topical formulations due to the tunable rheological characteristics and a simpler manufacturing process.

Source link: https://europepmc.org/article/MED/35569626


Assessment of plant species suitability in green walls based on API, heavy metal accumulation, and particulate matter capture capacity.

"A short-term solution to air pollution is to create green spaces, mainly green walls. " Using the air pollution tolerance index, estimate the tolerance level of plant species on green walls to air pollution; measure the PM capture on green wall species's leaves; and accumulation of heavy metals using inductively coupled plasma; select the most suitable species for reducing air pollution using the estimated performance index; and determine the most harmful species for lowering air pollution using estimated performance index. Among the APTI's key ingredients, leaf water content, and ascorbic acid had a positive effect on APTI. Carbon and oxygen were found in the elemental composition of PM deposited on the leaves of both species's leaves, according to EDX results, based on EDX results. The concentrations of all heavy metals tested in green wall plants were higher than in the control group.

Source link: https://europepmc.org/article/MED/35545746


BioExcel Building Blocks REST API (BioBB REST API), programmatic access to interoperable biomolecular simulation tools.

"Motivation" The BioExcel Building Blocks library has a large number of wrappers on top of common biomolecular simulation and bioinformatics equipment. BioBB REST API extends and complements the BioBB library that provides programmatic access to the BioBB library's collection of biomolecular simulation programs included in the BioExcel Building Blocks collection. Availability http://www. irbbarcelona. org/biobb-api/ has access to all of the BioBB REST API endpoints. Suppl's full workflow guide can be found in the Suppl. Links to extended documentation, including OpenAPI endpoints specification and examples, Read-The-Docs manual, and a complete workflow guide can be found in the Suppl.

Source link: https://europepmc.org/article/MED/35543460

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions