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"This research is designed to determine the effect of service quality on community satisfaction of passengers of the West Sumatra Divre 2 railroad service on the Padang-Pariaman route. " This type of study is a descriptive one that uses primary results as research results and stems from a questionnaire filled out by community members of the West Sumatra Divre 2 Railroad service, particularly the Padang-Pariaman route. The sampling procedure used is probability sampling using an accidental sampling technique. The five key indicators of service quality in PT KeretaApiDivre 2 West Sumatra - Padang route Pariaman are in both categories in terms of perception and expectation of service users, according to the study's findings. The findings revealed that the service provided by PT KeretaApiDivre 2 West Sumatra route Padang - Pariaman has provided good service to the people who use railroad services. ".
Source link: https://doi.org/10.24036/jmpe.v5i1.12778
"These APIs play a vital role in realizing the benefits of open data as they are the means by which data is discovered and accessed by applications that use it. " This paper discusses semantic APIsas as a means of increasing access to open data. The results show that theprobability of inter-country cooperation between open data catalogs is less than 30%, and that only a few categories stand out as candidates for a transnational semantic API.
Source link: https://doi.org/10.29379/jedem.v8i2.420
"Abstract API-1, a novel small-molecule inhibitor of Akt, acts by linking to Akt and preventing membrane translocation, and has promising preclinical antitumor activity. We present a new role of API-1 in the regulation of cell FLICE-inhibitory protein levels and TRAIL-induced apoptosis in this report, independent of Akt inhibition. API-1-based API-1 activated apoptosis in several experimental cancer cell lines, including activation of caspase-8 and caspase-9. These results indicate that c-FLIP mediates development of TRAIL-induced apoptosis by API-1 has decreased, but not enough to account for API-1-induced apoptosis in API-1. The proteasome inhibitor MG132 may have blocked API-1'u2013-induced c-FLIP reduction by the proteasome inhibitor MG132. API-1 is believed to have reduced c-FLIP and TPI-induced apoptosis while also increasing TRAIL-induced apoptosis independent of its Akt-inhibitory function, since other Akt inhibitors, such as API-2 and MK2206 had minimal effect on reducing c-FLIP and TRADIL-induced apoptosis, but it is likely that API-1 reduces c-FLIP and boosts TRAIL-inhibitory apoptos a apoptos apoptosis increasing apoptosis apoptosis, assay and apoptosis, including API-2 and apoptosis.
Source link: https://doi.org/10.1158/1940-6207.capr-11-0548
"Abstract During malignant glioma due to over stimulation of growth factor receptor receptors and increased regulation of the PI3K/Akt pathway, resistance to epidermal growth factor receptor inhibitors and pro-apoptotic agents is common. " With API-2, we were hoping to overcome glioblastoma cells' resistance to gefitinib by increasing autophagy cell death. We investigated whether combined gefitinib and API-2 enhanced DNA-PK signaling with EGFR and Akt, leading to decreased DNA-protein kinase-mediated DNA repair and autophagy. The combined gefitinib and API-2 therapy improved acridine orange staining and LC3-II expression in U251MG cells, with a further rise in combined gefitinib and API-2. Greater acridine orange staining by combined gefitinib and API-2 in MO59J was greater in MO59J than in MO59K cells. "Understandably impaired DNA repair of U251MG cells by Gefitinib and API-2," a patient's DNA is lost by the combination of gefitinib and API-2," causing even more inhibition by combined gefitinib and API-2.
Source link: https://doi.org/10.1158/1535-7163.targ-11-b240
"Abstract" means the American Petroleum Institute's crushing tests for proppant sizes used in recommended procedures are often used to determine the crack resistance of approved API proppant sizes at a predetermined stress under dry and humid conditions. ISO's "new" method gives no hint that the stress changes the overall mesh distribution. Incorporating these variables into a new API test strategy for crush resistance better mimics actual down-hole exposure to which a proppant is exposed. A standard API crush cell was modified for pressurized fluid flow at temperature and used to determine the effects of the parameters measured as compared to standard API crush tests. Modified testing results reveal critical proppant failures under conditions that more closely mimic those encountered downhole; these failures are not revealed by current standard API/ISO test methods;.
Source link: https://doi.org/10.2118/118929-ms
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