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Last Updated: 10 June 2022

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Elevated AST/ALT ratio is associated with all-cause mortality in patients with stable coronary artery disease: a secondary analysis based on a retrospective cohort study

"Abstract The aim of this study is to investigate the correlation between the aspartate amino transferase/alanine aminotransferase ratio and all-cause mortality in stable coronary artery disease patients undergoing percutaneous coronary intervention. " ACM was present in 6 patients in the low group and 12 patients in the high group, among them, with significant differences between the two groups. An elevated AST/ALT ratio in stable ACD patients was correlated with increased ACM in the Kaplan/u2013Meier study. Therefore, an elevated AST/ALT ratio in stable ACD patients is an independent prognostic factor for ACM.

Source link: https://doi.org/10.1038/s41598-022-13355-2


Elevation of AST/ALT Ratio in Association with Severity of Esophageal Varices in Patients with Hepatic Cirrhosis

"Objective: To determine the AST/ALT ratio in association with the occurrence of esophageal varices in patients with hepatic cirrhosis. One hundred and ten patients were enrolled in the study Design: Cross sectional survey Place and Time: Medical Unit II, Jinnah Hospital Lahore, from November 2018 to April 2019, Methodology: One hundred and ten participants were enrolled. The majority of esophageal varices in 30 patients of liver cirrhosis were found to have a 27% risk of esophageal varices. "The elevated ALT and AST are strongly associated with the occurrence of esophageal varices in hepatic cirrhosispatients" (asthopathosy).

Source link: https://doi.org/10.53350/pjmhs22165259


AST/ALT (De Ritis) Ratio in Early Stage Differentiated Thyroid Cancer

"Objective: Differentiated thyroid cancers are the most common endocrine cancers, and their incidence is on the rise in imaging techniques. Method: The analysis included a total of 154 patients diagnosed with differentiated thyroid cancer in our clinic between 2016 and 2019. According to the American Joint Cancer Committee 8, Tumor staging of each patient was carried out by measuring the postoperative pathology findings. The connection between the patients' preoperative De Ritis rates and postoperative staging was investigated. The prevalence of patients with De Ritis disease (u22651. 5) was 15. 9%. "In our analysis, it was found that preoperative De Ritis ratio was not related to disease stage and risk status in early stage differentiated thyroid cancers. ".

Source link: https://doi.org/10.30934/kusbed.1009993


External validation of preoperative AST/ALT (De-Ritis) ratio as a prognostic indicator in localized and metastatic renal cell carcinoma.

"589 Background: The De-Ritis ratio, a ratio of preoperative aminotransferase to alanine aminotransferase, has been shown to be a reliable predictor of overall and recurrence-free survival in a European cohort with localized renal cell carcinoma. In this research, we perform an external validation of the De-Ritis ratio as a prognostic indicator in a specific group of patients with localized and metastatic RCC. Patients with nephrectomy for localized and metastatic RCC between 2001 and 2014 were tested from the Emory Nephrectomy Database within one week of surgery. Prognostic value of the De-Ritis ratio was calculated using the Kaplan-Meier method and Cox proportional regression models, based on clinical follow-up results. Conclusions: Elevated De-Ritis ratio is a reliable and reliable predictor of overall and recurrence-free survival and is capable of distinguishing high-risk disease in patients with localized and metastatic RCC. ".

Source link: https://doi.org/10.1200/jco.2016.34.2_suppl.589


The significance of transaminase ratio (AST/ALT) in acute myocardial infarction

"We wanted to investigate the AST/ALT ratio changes in patients with acute myocardial infarction in China Han patients with no history of liver diseases. " Material and methods We investigated a total of 120 patients with acute myocardial infarction admitted to Zhongnan Hospital of Wuhan University between January 2019 and June 2019. The first blood test's AST/ALT ratio was calculated for all patients. Patients with ST-segment elevation myocardial infarction were more likely than in non-ST-segment elevation myocardial infarction patients.

Source link: https://doi.org/10.5114/amsad.2020.103028


Impact of pesticide residues (chlorpyrifos, cypermethrin, profenophos) on health and liver marker values alkaline phosphate (ALP), alanine amino transferase (ALT) and (AST) among workers of pesticide formulation & packing plants in Pakistan

Methods: In the present study, a hundred workers of 20-50 years of operation, aspartate amino transferase, and alanine amino transferase among workers of pesticide manufacturing and packaging plants in Pakistan were included. Pesticide residues were investigated using the gas chromatograph electron capture device GCECD 2010, Shimadzu Japan, and pesticide residues were removed from the lab. In the most recent report, 100 workers of the pesticide industry were recruited, and ALP, AST, and ALT of 80 workers out of 100 were found to be within the acceptable limits. However, 20 employees had unexpectedly elevated ALP ALT and AST levels. Conclusions: All the employees' pesticide residue levels were extremely poor, and they were not sufficiently significant to cause health issues. ".

Source link: https://doi.org/10.53350/pjmhs22164223

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions