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ADHD Autism - Europe PMC

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Last Updated: 16 April 2022

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Developmental Changes of Autistic Symptoms, ADHD Symptoms, and Attentional Performance in Children and Adolescents with Autism Spectrum Disorder.

This review compared ADHD/autistic symptoms and attentional growth in children/adolescents with ASD and those with adolescents with ASD and more typical ones over 5-7 years. The children with ASD showed the most improvement in reaction time, while ASD students had less improvement in commission errors and detectability than TD. The absence of a correlation between attentional skills and ADHD in ASD revealed different neural pathways of ADHD symptoms in ASD.

Source link: https://europepmc.org/article/MED/35420295


Multivariate base rates of score elevations on the BRIEF2 in children with ADHD, autism spectrum disorder, or specific learning disorder with impairment in reading.

Attention Deficit Hyperactivity Disorder (BRM) Inventory of Executive Function, Second Edition for several clinical groups; ADHD Inattentive Presentation ; Autism Spectrum Disorder; and Specific Learning Disorder with impairment in Reading are examples. Cumulative MBRs were tested for each BRIEF2 stage and at three T -score cutoffs. At T 60, T 65, and T 70, the MBR of obtaining at least one excellent score was common across clinical groups and forms at T 60, T 65, and T 70. To improve clinical interpretation of BRIEF2 results, we provide new MBR results to aid in the interpretation of BRIEF2 results.

Source link: https://europepmc.org/article/MED/35379083


Plasma and red blood cell n3 fatty acids correlate positively with the WISC-R verbal and full-scale intelligence quotients and inversely with Conner's parent-rated ADHD index t-scores in children with high functioning autism and Asperger's syndrome.

The results of the diagnosis of autism spectrum disorders' fatty acid status have been incongruent, perhaps due to the diversity of the condition. In a homogenous group of children with autism spectrum disorder, a cross-sectional design study was used to investigate fatty acid levels and relationships between fatty acids, as well as cognition and behavior. Plasma phosphatidylcholine 22:5n3 with verbal and full scale IQs, red blood cell phosphatidylcholine 22:5n3 with verbal, performance, and full scale IQs, and red blood cell phosphatidylethanolamine 22:5n3 with verbal and full scale IQs were found in the AS group, with verbal and full IQs, verbal, performance, and full scale IQs, The pH of plasma phosphatidycholine 20:5n3, 22:6n3 and total n3 fatty acids, red blood cell phosphatidylethanolamine 20:5n3 and total n3 fatty acids are correlated inversly with ADHD index, with plasma phosphatidycholine 20:5n3, 22:6n3 and total n3 fatty acids correlated inversly with ADHD index, inversly phosphati Hyperactivity and red blood cell phosphatidylcholine 18:4n6 and performance and complete IQs are shown by inverse correlations between red blood cell phosphatidylcholine 18:4n6 and inattention, as shown by inverse correlations between red blood cell phosphatidylcholine 22:4n6 and inattention, between red blood cell phosphatidylcholine 22:4n6 and inattention, as well as in Positive correlations were found between 22:5n3 and cognition, as well as negative relationships between 20:6n3 and behavioural disorder, according to the results of the ethnically homogenous children with Asperger's syndrome/high functioning autism study.

Source link: https://europepmc.org/article/MED/35338846


CHAMP1 disorder is associated with a complex neurobehavioral phenotype including autism, ADHD, repetitive behaviors and sensory symptoms.

CHAMP1 disorder, or CHAMP1 syndrome, is a newly identified developmental disorder that is associated with developmental delay, intellectual impairment, psychosocial disorders, medical comorbidities, and dysmorphic signs. Based on about 12 hours of remote clinician-administered surveys and standardized caregiver questionnaires, we present deep phenotyping findings for 11 individuals with CHAMP1 disorder. To 33% of participants, autism spectrum disorder was diagnosed; repetitive habits and sensory-seeking symptoms were common in this cohort. High prevalence of ADHD and relatively low rates of treatment suggest potential areas for intervention. This report is the first prospective phenotyping review of people with CHAMP1 disorder.

Source link: https://europepmc.org/article/MED/35271727


Parent-reported Early Atypical Development and Age of Diagnosis for Children with Co-occurring Autism and ADHD.

This study, which included 288 New Zealand parents of autism, ADHD, or both disorders, looked at the correlations between diagnosis and early atypical growth, as well as types of specialists seen. Autism and ADHD were related to an earlier ADHD diagnosis and a later autism diagnosis.

Source link: https://europepmc.org/article/MED/35254600


Enhancing the Discriminatory Power of ADHD and Autism Spectrum Disorder Polygenic Scores in Clinical and Non-Clinical Samples

Objective Polygenic scores are increasingly used in psychiatric genetic association studies due to their ability to predict focal outcomes. The aim of the study was to improve the discriminatory ability of psychiatric PGS for two highly comorbid and genetically linked neurodevelopmental disorders in ADHD and autism spectrum disorder. In two large independent studies, the Philadelphia Neurodevelopmental Cohort and the Simons Foundation Powering Autism Research for Knowledge ASD and sibling controls cohort were tested. In addition, genetic correlations between GenomicSEM PGS for ASD and ADHD were strikingly impaired in cross-trait relationships with other psychiatric disorders and outcomes. Conclusions The psychiatric PGS associations are inflated due to the high degree of genetic overlap between the psychiatric disorders.

Source link: https://europepmc.org/article/PPR/PPR452763

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions