* If you want to update the article please login/register
Abstract Background - Attention deficit hyperactivity disorder and trait impulsivity have been linked to disordered eating but have never been measured in community studies or longitudinally, and no information about the mediating mechanisms is known about the mediating mechanisms. Methods We investigated relationships between ADHD symptoms and disordered eating cross-sectionally and between trait impulsivity and disordered eating longitudinally. Using the SCOFF system, participants were classified as high risk or low risk of disordered eating. In the third step, adult ADHD self-report scale scores, separated into inattentive and hyperactive/impulsive signs, were used for the cross-sectional analysis. Attentional impulsivity and the disordered eating risk was partially mediated by MFQ scores, although the connection between disturbances in hunger and the disordered eating risk was largely mediated by MFQ findings. These results point to a specific role for ADHD inattentive symptoms and the importance of both depression and impulsivity in predicting eating disorder risk.
Source link: https://doi.org/10.1017/s0033291720004638
Conclusions The delayed sleep phase has been shown to occur in several children and in around 80% of adults with ADHD. Adult patients with ADHD who wake up much too early for breakfast tend to skip breakfast. Both binge eating and skipping breakfast have been attributed to excess and obesity in the afternoon, and skipping breakfast has been associated with binge eating in the afternoon. Conclusions ADHD and the extremely rare comorbid delayed sleep phase disorder may be related to a delayed diet that may lead to hunger and obesity.
Source link: https://doi.org/10.1016/s0924-9338(10)70005-5
Objects We will discuss the findings of a systematic review of methylphenidate's use in adult ADHD treatment. Methods We searched Medline, PsycINFO, and CCTR to find randomised controlled clinical trials comparing methylphenidate with placebo in the treatment of adult ADHD. Subgroup studies were conducted with respect to parallel group vs. cross-over trials and self vs. observer ratings. Weighted regression analysis showed that the relationship between dose and effect size was investigated. The regression results showed that there was no significant effect of the mean daily dose on effect size.
Source link: https://doi.org/10.1016/s0924-9338(10)70880-4
Methods Multicenter randomizing adult subjects with ADHD who underwent open-label treatment with OROS MPH for at least 52 weeks and agreed to a 4-week, double-blind, placebo-controlled withdrawal period. Patients recovered after 99/155 patients completed the OL OROS MPH therapy phase, but only 45/99 patients consented to double-blind randomization. Meant u00b15. 34 in the continuing OROS MPH group and 16. 5 percent in the placebo group at 12. 1°u00b17. 49. CAARS transformed from DB baseline to DB endpoint by 4. 0. 61 and 6. 5. 82, respectively, when converting from DB baseline to DB endpoint. In comparison to the ongoing PR OROS MPH, more symptoms in the placebo group correlated to greater severity of symptoms. The primary outcome may have been based on a random withdrawal process, which may have failed to establish statistical correlation between treatment groups. Conclusions The study shows that after long-term exposure of adults with ADHD to OROS MPH, there is a risk of medical symptoms that persists.
Source link: https://doi.org/10.1016/s0924-9338(10)70952-4
The inhibition of prepotent response tendencies is both apparent in medial frontal and lateral frontal BOLD responses. The aim of this simultaneous EEG and fMRI study was to determine the neural correlates of ADHD-related behaviours. During the go condition, eight adults with ADHD and eight healthy people under similar circumstances underwent a go/nogo test involving three distinct conditions: during the go condition, participants were instructed to press a response button as quickly as possible; in the nogo situation, this response was to be discouraged. In the pre-SMA and activations in BA 8's medial portion of the voluntary selection, we found inhibition-associated BOLD responses particularly medial-frontal. Compared to controls, ADHD patients with ADHD showed a reduced presence of frontal brain regions during free responses. ADHD patients with disabilities primarily in frontal brain regions. The findings may indicate that selection processes are related to learning difficulties that are primarily in frontal brain regions.
Source link: https://doi.org/10.1016/s0924-9338(10)70764-1
Latent Inhibition is a robust phenomenon that is demonstrated when a previously insignificant stimulus is less effective in a new learning situation than a novel stimulus. Attentional studies of a LI state show that unattended stimulus preexposures reduce stimulus salience and subsequent associability. Since dopamine-agonists weaken the LI effect, dopamine-agonists weaken the LI effect, and dopamine antagonists boost it, a connection between LI and the dopaminergic system has been proposed. Since dopamine agonists will reduce LI, pharmacist agonists can depress LI, dopamine agonists can deteriorate LI, but the increase in focus may stifle it. The ADHD patients will be included in the first version of the therapy without medication and in the second version 1. 5 hours after taking the drugs; the time interval between versions will be the same as between versions, but without the medication administration.
Source link: https://doi.org/10.1016/s0924-9338(10)70006-7
ADHD symptoms in adults have been debated largely. In a sample of 600 ADHD patients, a correlation between the scales and emotional content in the Wender-Reimherr Adult Attention Deficit Disorder Scale was investigated relative to other existing ADHD rating scales. The aim is to determine whether the symptoms are related to other ADHD domains.
Source link: https://doi.org/10.1016/s0924-9338(10)70026-2
We used a computer software developed by Bundesen to compare two groups of adults with ADHD and a matched healthy control group in order to more precisely identify the affected and preserved attentional components in adults with ADHD. The WM storage capacity was reduced in medicated patients, but was still much worse than normal controls. Attentional weights are altered in the case that unmedicated ADHD patients did not exhibit the expected preference for the left visual hemisphere. In conclusion, the attentional core deficit in ADHD seems to be a decrease in WM storage capacity, i. e. Since no deficiencies in speed and top-down control have been established, the failure of response-based tasks may have more reflect deficiencies in the initiation, execution, and inhibition of motor responses than impairments on the level of perceptual processing.
Source link: https://doi.org/10.1016/s0924-9338(10)71535-2
Objective Increasing evidence shows that Attention Deficit Hyperactivity disorder (TDH) disorder symptoms can persist into adult life in a significant number of cases. In a sample of 110 Caucasian patients, the aim of the present study is to investigate the effects of 1 adverse event, two personality traits, and three genetic variants selected on the basis of previous findings and four of their possible interactions on adult ADHD in a sample of 110 Caucasian patients. Methods The Temperament and Character Inventory TCI examines one hundred and ten people with adult ADHD, as well as personality traits. Results Genetic variations were not significantly related to ADHD symptoms and life stressors, resulting in only a minor effect as compared to personality traits. Conclusions: The present findings are in accordance with previous reports of a strong association between some personality traits and adult ADHD.
Source link: https://doi.org/10.1016/s0924-9338(10)71567-4
In a five-week, double blind, fixed dose, placebo controlled study in adults with ADHD, the aim of this research was to investigate the relationship between symptomatic and functional outcomes. Methods A five-week, double-blind, parallel arm, placebo-controlled trial in adult subjects with ADHD and a Conners'u2019 Adult ADHD Rating Scale score >= 24 at baseline. Pearson's partial correlation analysis evaluated CAARS' relationship with SDS and Q-LES-Q, with adjustment for baseline scores of CAARS, SDS, Q-LES-Q, CGI-S, age, sex, and randomization group. At the endpoint for both OROS MPH treatment groups compared to placebo, there was a significant therapeutic effect as measured in TCS at the DB endpoint. Conclusion Subjectsu2019 symptomatic improvements during PR OROS MPH therapy are evident in changes in their professional and social life as reflected by the SDS and quality of life.
Source link: https://doi.org/10.1016/s0924-9338(10)70979-2
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions