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Background: Cognitive impairment is a well-documented predictor of change to a full-threshold psychotic disorder amongst individuals at an extremely high risk of psychosis. However, it is also unknown if change in cognitive function varies between those who do and do not transition to a psychotic disorder, while others who do and do not change to a psychotic disorder. To date, there haven't been studies into trajectories in intelligence constructs, which have found significant differences in people with schizophrenia. Methods: Participants at UHR's psychosis supervised the Wechsler Abbreviated Scale of Intelligence at each follow-up. There were no significant differences in trajectories between those who did and did not transition to psychosis or those with high and poor functional results. As the small sample of people who moved may have limited our ability to detect subtle differences, future studies with larger sample sizes are required to investigate potential differences in intelligence trajectories between UHR transition groups.
Source link: https://europepmc.org/article/PPR/PPR421641
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