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"CAV3-related distal myopathy is just one of many disorders characterized by a lack of muscle mass and general lack of function affecting the muscles farther away from the body's center of the body, such as those of the hands and feet. " People with CAV3-related distal myopathy experience wasting and apathy of the small muscles in the hands and feet that are usually present in adulthood. The calf muscles can overgrowth may also occur in CAV3-related distal myopathy.
"Rippling muscle disease is a disorder in which the muscles are exceptionally sensitive to movement or pressure. " Stretching the muscle tissue creates visible ripples that spread throughout the body, lasting 5 to 20 seconds in most people with this disease. Overgrowth of certain muscles, particularly in the calf, may be present in people with a rippling muscle disease. The age of onset of rippling muscle disease in late childhood or adolescence varies widely, but it usually starts in late childhood or adolescence. Rippling muscles may also be a result of other muscle disorders, such as leg-girdle muscular dystrophy," according to a limb-girdle muscular dystrophy.
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