* If you want to update the article please login/register
BACKGROUNDING BACKGROUND ISLAND XIA infants with profound T lymphopenia, as seen in cases of severe combined immunodeficiency and in a subgroup of infants with 22q11 deletion syndrome reveals infants with profound T lymphopenia. The 22q11Low group had lower numbers of nave T-helper cells, na've T-regulatory cells, nave cytotoxic T cells, nave cytotoxic T cells, and gradually reduced TRECs compared to healthy controls as compared to healthy controls. Compared to nave cytotoxic T cells, shorter RTL, and a trend toward higher clonality were found for nave T-helper cells in nave T-helper cells, according to skewed V-gene use for nave T-helper cells, despite a trend towards increased clonality in the nave T-helper cells. In both the 22q11Low and 22q11Normal groups, there were greater numbers of nave B cells and lower amounts of memory B cells, as well as switched memory B cells.
Source link: https://doi.org/10.1007/s10875-021-01201-5
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions