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1 Degree - Europe PMC

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Last Updated: 02 July 2022

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Automated 360-degree goniophotography with the NIDEK Gonioscope GS-1 for glaucoma

When used to classify the iridocorneal angle in a clinical setting, the objective was to determine the fidelity of the NIDEK Gonioscope GS-1. Methods An online database of 20 participants who were 18 or older, had glaucoma, or were glaucoma survivors, was accepted by the NYU Langone Eye Center and Bellevue Hospital. Independent expert observers alike judged automated 360-degree goniophotography using the NIDEK Gonioscope GS-1's quality such that they are interpreted similarly by automated expert observers. Result Images obtained from automated 360-degree goniophotography using the NIDEK Gonioscope GS-1 have been similarly interpreted amongst glaucoma specialists, thereby enabling the use of this technology to document and evaluate the anterior chamber angle in patients with glaucoma and iridocorneal angle abnormalities. The NIDEK Gonioscope GS-1 is a useful tool for anterior chamber angle determination, as shown by the Prism Automated 360-degree goniophotography.

Source link: https://europepmc.org/article/PPR/PPR509663


Autoantibodies against ATP4A are a feature of the abundant autoimmunity that develops in first-degree relatives of patients with type 1 diabetes.

Objective Type 1 diabetes is related to autoantibodies in various organs, including the stomach. The aim of the study was to determine the risk of developing gastric parietal cell autoimmunity in people with a family history of type 1 diabetes. Methods Autoantibodies to the parietal cell autoantigen, H+/K + ATPase subunit A was analyzed in 2218 first-degree relatives of patients with type 1 diabetes who were prospectively followed from birth for a median of 14. 5 years. In females, relatives of the HLA DR4-DQ8/DR4-DQ8 genotype, and in participants with thyroid peroxidase autoantibodies, the risk was heightened in females, relatives, and participants with thyroid peroxidase autoantibodies. Conclusions Relatives of patients with type 1 diabetes and risk genotypes are at a high risk of autoimmunity against gastric and other organs.

Source link: https://europepmc.org/article/MED/35561070

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions